{"id":"W2609935796","doi":"10.1161/hyp.66.suppl_1.p062","title":"Abstract P062: Long-term Exposure to Endothelin-1 Overexpression Increases Blood Pressure and Causes Small Artery Injury","year":2015,"lang":"en","type":"article","venue":"Hypertension","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Endocrinology; Internal medicine; Endothelin receptor; Endothelin 1; Blood pressure; Aldosterone; Medicine; Kidney; Myograph; Tamoxifen; Endothelium; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002155822,0.0008124966,0.0006200268,0.0004060717,0.0002282369,0.0004012869,0.0003446894,0.0007080882,0.009670116],"category_scores_gemma":[0.0001993313,0.0002094073,0.0004615073,0.0002202808,0.0004883896,0.0004756121,0.0003087696,0.001665516,0.001879118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002668244,"about_ca_system_score_gemma":0.0001717398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002268674,"about_ca_topic_score_gemma":0.0002587452,"domain_scores_codex":[0.99976,0.00002078363,0.00002426406,0.00006400195,0.00008059217,0.00005039848],"domain_scores_gemma":[0.9995806,0.00004393092,0.0001325512,0.0000295856,0.00003597134,0.0001774774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005224374,0.0001110188,0.0003604062,0.00006479285,0.000009485594,0.000241062,0.00001337989,0.00001026763,0.9968755,0.00005128989,0.000216596,0.001523746],"study_design_scores_gemma":[0.0002465096,0.003810363,0.04113608,0.00006452113,0.0001102745,0.00508084,0.000144009,0.0006063406,0.9412389,0.0001640238,0.007377612,0.00002059641],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988794,0.002020947,0.003531993,0.0007259559,0.0002874843,0.0000516055,0.001510001,0.0002611672,0.002816802],"genre_scores_gemma":[0.9587317,0.002706632,0.003480053,0.0005279449,0.0003158519,0.0002090195,0.003928477,0.0001693016,0.02993103],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009670116,"threshold_uncertainty_score":0.03234977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03523739901461876,"score_gpt":0.2601214368512375,"score_spread":0.2248840378366187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}