{"id":"W2610134874","doi":"10.1136/rmdopen-2017-000430","title":"Effect of certolizumab pegol over 96 weeks of treatment on inflammation of the spine and sacroiliac joints, as measured by MRI, and the association between clinical and MRI outcomes in patients with axial spondyloarthritis","year":2017,"lang":"en","type":"article","venue":"RMD Open","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"UCB Pharma","keywords":"Medicine; Certolizumab pegol; Ankylosing spondylitis; Axial spondyloarthritis; Placebo; Spondylitis; Internal medicine; Magnetic resonance imaging; Gastroenterology; Sacroiliitis; Surgery; Nuclear medicine; Radiology; Disease; Pathology; Adalimumab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003756793,0.0001563247,0.0008221394,0.00002957438,0.000133838,0.0000286884,0.00009429649,0.00008548639,0.000007519583],"category_scores_gemma":[0.0004754851,0.00007687784,0.00006647004,0.00003664142,0.0002634314,0.00009846055,0.0001475407,0.0000834706,4.996453e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006791343,"about_ca_system_score_gemma":0.00003130214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001705727,"about_ca_topic_score_gemma":0.0006351309,"domain_scores_codex":[0.9987514,0.0002306744,0.0004068229,0.0002029333,0.0002881686,0.0001200176],"domain_scores_gemma":[0.9987609,0.0002670205,0.000526907,0.0003285272,0.00007405521,0.00004262701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002430308,0.0001381972,0.9711121,0.0000418025,0.000378214,0.000002785375,0.000256202,8.288735e-8,0.00001894294,0.00002411309,0.00002841366,0.02556885],"study_design_scores_gemma":[0.05877468,0.005201542,0.9340435,0.0003182393,0.0003350287,0.000001987283,0.00001968047,0.000002939897,0.001098083,0.00003216512,0.0001133529,0.00005879613],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962175,0.0002200784,2.45111e-7,0.001011233,0.00005082394,0.00194615,0.0001182424,0.000002216299,0.0004334501],"genre_scores_gemma":[0.9992425,0.0004797416,0.00001699215,0.000009495825,0.00002077628,0.00003822572,0.00002155026,0.00001044506,0.0001602083],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05634438,"threshold_uncertainty_score":0.3134987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01309326834894052,"score_gpt":0.3078321687806808,"score_spread":0.2947389004317402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}