{"id":"W2610179240","doi":"10.1038/nsmb.3406","title":"Splicing of Ezh1 gets muscle out of stressful situations","year":2017,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Stem Cell Network; Ottawa Hospital; University of Ottawa","funders":"","keywords":"PRC2; EZH2; Cell biology; Histone; RNA splicing; Biology; Epigenetics; Histone methyltransferase; Alternative splicing; Gene; Chemistry; Genetics; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001158412,0.0001666481,0.0002434183,0.00005665163,0.0001292559,0.00001297997,0.0004075718,0.0005314557,0.00001247666],"category_scores_gemma":[0.0003203714,0.0001472484,0.0001482292,0.00002666407,0.000229286,0.000004533375,0.000199811,0.0001983163,9.184564e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006846244,"about_ca_system_score_gemma":0.0000480649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005079267,"about_ca_topic_score_gemma":0.0001017396,"domain_scores_codex":[0.9989922,0.00007110069,0.0002893006,0.0003331268,0.0001088809,0.000205399],"domain_scores_gemma":[0.9985403,0.00001186661,0.0004092041,0.0007470874,0.0002382053,0.00005335466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002300018,0.000008560714,0.00470432,0.00001795794,0.00005932384,0.000001639224,0.00004055201,0.00008495962,0.9867815,0.0015628,0.00001481976,0.00670053],"study_design_scores_gemma":[0.000373018,0.0001954218,0.05030238,0.00001248619,0.00003088225,0.000001075458,0.00001543448,0.00006266354,0.9420665,0.005319198,0.001472262,0.0001486967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930567,0.00241007,0.002486154,0.0003403857,0.0004383985,0.0001598004,0.0000761276,0.000005192557,0.00102722],"genre_scores_gemma":[0.997107,0.0001723901,0.002236582,0.00005717769,0.0001249534,0.000003934822,0.0002143287,0.00001694082,0.00006670575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04559806,"threshold_uncertainty_score":0.6004617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008190542858805248,"score_gpt":0.3355162736726854,"score_spread":0.3273257308138802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}