{"id":"W2610267472","doi":"10.1016/j.bbagen.2017.05.004","title":"Characterization of constitutive and acid-induced outwardly rectifying chloride currents in immortalized mouse distal tubular cells","year":2017,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - General Subjects","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"British Heart Foundation; McGill University; Canadian Institutes of Health Research; University of Connecticut; Harvard University","keywords":"DIDS; Niflumic acid; Chemistry; Extracellular; Chloride channel; Reabsorption; Biophysics; Hyperpolarization (physics); Flufenamic acid; Channel blocker; Membrane potential; Biochemistry; Endocrinology; Stereochemistry; Kidney; Membrane; Biology; Calcium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003096233,0.0003275371,0.0004423466,0.0003447649,0.0002145146,0.0004987873,0.0004494971,0.0004037559,0.0009546071],"category_scores_gemma":[0.0002325278,0.0002215194,0.0006199893,0.000396288,0.0002975744,0.0003866451,0.0002491237,0.000862824,0.0009049265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002566387,"about_ca_system_score_gemma":0.0002149414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005391334,"about_ca_topic_score_gemma":0.0005007493,"domain_scores_codex":[0.9996854,0.00002661786,0.00005966331,0.00006760649,0.0000993642,0.00006129736],"domain_scores_gemma":[0.9997388,0.0000483996,0.00005290032,0.00005780836,0.00004940897,0.00005266534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002294848,0.000008022271,0.00008442753,0.00001702252,0.000002378935,0.00004240577,0.00001818844,0.00001255104,0.9995479,0.00004190877,0.000007228473,0.0001949102],"study_design_scores_gemma":[0.00001798199,0.0001786877,0.006795511,0.000006699008,0.00003852763,0.0005897984,0.00006536307,0.0008277692,0.9875811,0.00005267495,0.003836174,0.000009661311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9735096,0.003060278,0.01894725,0.0001376605,0.00006494216,0.0001083098,0.002477884,0.0002867029,0.001407343],"genre_scores_gemma":[0.9717048,0.003421204,0.01095636,0.0001201654,0.00005896435,0.0002460304,0.007344166,0.0001356947,0.006012586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009546071,"threshold_uncertainty_score":0.003193438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01568039593102552,"score_gpt":0.2617012233532316,"score_spread":0.2460208274222061,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}