{"id":"W2610280068","doi":"10.1002/ijc.30764","title":"RAD51 as a potential surrogate marker for DNA repair capacity in solid malignancies","year":2017,"lang":"en","type":"review","venue":"International Journal of Cancer","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Krebsliga Schweiz; Public Health Agency of Canada","keywords":"Surrogate endpoint; RAD51; DNA repair; DNA; Medicine; Cancer research; Biology; Genetics; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009591934,0.0008734381,0.00152507,0.00366097,0.0002372018,0.0009653341,0.0009831613,0.001173856,0.002214786],"category_scores_gemma":[0.001378653,0.0003231825,0.0006312645,0.002461548,0.0006538215,0.001353438,0.0006377611,0.001919848,0.001435519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007608091,"about_ca_system_score_gemma":0.0009124672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008146942,"about_ca_topic_score_gemma":0.001162609,"domain_scores_codex":[0.9996905,0.00006012371,0.00005526577,0.00006605483,0.0001054911,0.00002258767],"domain_scores_gemma":[0.9992455,0.0004562498,0.00008942642,0.00002111455,0.0001514211,0.00003626946],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001150259,0.00005485717,0.0007226405,0.01697884,0.0001339786,0.0002245927,0.00005397745,0.000322703,0.002049707,0.003188223,0.01715534,0.959],"study_design_scores_gemma":[0.00002188295,0.0001731438,0.003313885,0.006283964,0.0003135176,0.003269777,0.00008706941,0.0001898007,0.001816366,0.003028364,0.9814568,0.00004557012],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001082091,0.9989744,0.0001161605,0.0001746446,0.0001484642,0.000003422418,0.00001832242,0.00000431613,0.0004520383],"genre_scores_gemma":[0.001034518,0.9980922,0.000186807,0.0001528893,0.0001445876,0.000006499142,0.00004684016,0.000001686002,0.0003339043],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00366097,"threshold_uncertainty_score":0.007409215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06033860414692218,"score_gpt":0.3877054736373871,"score_spread":0.3273668694904649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}