{"id":"W2610732087","doi":"10.1016/j.phytochem.2017.04.019","title":"The ATP binding cassette transporter, VmTPT2/VmABCG1, is involved in export of the monoterpenoid indole alkaloid, vincamine in Vinca minor leaves","year":2017,"lang":"en","type":"article","venue":"Phytochemistry","topic":"Alkaloids: synthesis and pharmacology","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Brock University","funders":"Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; Genome Canada; Brock University; Ontario Ministry of Research, Innovation and Science; Canada Research Chairs; McGill University; University of Calgary","keywords":"Apocynaceae; Catharanthus roseus; ATP-binding cassette transporter; Indole alkaloid; Transporter; Vindoline; Biology; Alkaloid; Efflux; Vinca; Subfamily; Biochemistry; Secretion; Botany; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001141205,0.000415233,0.0005880183,0.00007945746,0.0006911431,0.00004919864,0.001719341,0.0005304337,0.0005315759],"category_scores_gemma":[0.0001676704,0.0003069281,0.0002568399,0.0001884326,0.0008357447,0.0001727224,0.000273911,0.001288175,0.00002411163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001609317,"about_ca_system_score_gemma":0.0002082143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002151261,"about_ca_topic_score_gemma":0.0004369814,"domain_scores_codex":[0.9972726,0.0002486747,0.0008911912,0.0005508922,0.0002646988,0.0007719792],"domain_scores_gemma":[0.9975947,0.0005554825,0.0007135185,0.0009081224,0.00007158048,0.0001565548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004570006,0.000318219,0.3119979,0.0001150103,0.0001205995,0.00005775251,0.001215452,0.00001832352,0.6796626,0.00001782703,0.002018392,0.00400092],"study_design_scores_gemma":[0.002281923,0.00003178923,0.1261767,0.00007988424,0.00009084517,0.00001370667,0.0003340289,0.0003134668,0.8512409,0.0001873006,0.01892433,0.0003250841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909872,0.001067147,0.000003451898,0.003040094,0.0008085189,0.0005844945,0.00013493,0.00002329448,0.003350874],"genre_scores_gemma":[0.9963705,0.0005642199,0.00002469394,0.0009639944,0.0002966692,0.0001878778,0.00001428078,0.00004306331,0.001534683],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1858212,"threshold_uncertainty_score":0.9999383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08677365207200453,"score_gpt":0.3975096478780917,"score_spread":0.3107359958060872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}