{"id":"W2610732087","doi":"10.1016/j.phytochem.2017.04.019","title":"The ATP binding cassette transporter, VmTPT2/VmABCG1, is involved in export of the monoterpenoid indole alkaloid, vincamine in Vinca minor leaves","year":2017,"lang":"en","type":"article","venue":"Phytochemistry","topic":"Alkaloids: synthesis and pharmacology","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Brock University","funders":"Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; Genome Canada; Brock University; Ontario Ministry of Research, Innovation and Science; Canada Research Chairs; McGill University; University of Calgary","keywords":"Apocynaceae; Catharanthus roseus; ATP-binding cassette transporter; Indole alkaloid; Transporter; Vindoline; Biology; Alkaloid; Efflux; Vinca; Subfamily; Biochemistry; Secretion; Botany; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005132025,0.0001640291,0.0002799218,0.0001804377,0.0002707212,0.0004901551,0.0002171577,0.0004343058,0.001039245],"category_scores_gemma":[0.000101825,0.0001814565,0.0002121202,0.0001460739,0.0001422405,0.0003475145,0.0001502775,0.0004182042,0.0004943751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006158245,"about_ca_system_score_gemma":0.000235322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002685848,"about_ca_topic_score_gemma":0.002528527,"domain_scores_codex":[0.999927,0.000006423472,0.000005195025,0.00002835456,0.00001604336,0.00001682635],"domain_scores_gemma":[0.9999328,0.000008517578,0.00001852326,0.000005699484,0.00001462183,0.00001981703],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006560484,0.000005411021,0.0003404821,0.00001938225,0.000002258635,0.00003585888,0.000009087953,0.00002145864,0.9987636,0.0001056322,0.00005456553,0.0005767217],"study_design_scores_gemma":[0.00003055763,0.0001077444,0.06486341,0.0000153768,0.00003444055,0.001192703,0.0001693825,0.007438532,0.9185366,0.0002684153,0.007325687,0.00001711233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943067,0.001053811,0.00271455,0.0002437891,0.00002134069,0.00001005981,0.000549086,0.0001069534,0.0009936178],"genre_scores_gemma":[0.9942269,0.0002222607,0.0009510267,0.000059279,0.000006596487,0.000006343301,0.0008290356,0.00003570076,0.003662825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002685848,"threshold_uncertainty_score":0.005340397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08677365207200453,"score_gpt":0.3975096478780917,"score_spread":0.3107359958060872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}