{"id":"W2610914955","doi":"10.1016/j.bbmt.2017.04.026","title":"Recommendations for Screening and Management of Late Effects in Patients with Severe Combined Immunodeficiency after Allogenic Hematopoietic Cell Transplantation: A Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric HCT","year":2017,"lang":"en","type":"review","venue":"Biology of Blood and Marrow Transplantation","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Center for Advancing Translational Sciences; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Cancer Institute; National Heart, Lung, and Blood Institute; St. Baldrick's Foundation","keywords":"Medicine; Transplantation; Hematopoietic cell; Hematopoietic stem cell transplantation; Severe combined immunodeficiency; Intensive care medicine; Newborn screening; Pediatrics; Haematopoiesis; Internal medicine; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032223,0.0004717718,0.0009636885,0.0002393193,0.0001883677,0.00002527085,0.0002353892,0.000341991,0.00003547656],"category_scores_gemma":[0.000005474928,0.0003496793,0.0001404582,0.00009390144,0.0003117514,0.0000777698,0.00002868585,0.000293243,0.000001254217],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007342971,"about_ca_system_score_gemma":0.0000612791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004316918,"about_ca_topic_score_gemma":0.00003024367,"domain_scores_codex":[0.9977817,0.0003832665,0.0008684183,0.0005677668,0.00006800435,0.000330822],"domain_scores_gemma":[0.9982387,0.0007367313,0.0006932192,0.0002444781,0.00006917674,0.00001765069],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"observational","study_design_scores_codex":[0.0370285,0.007765007,0.2985311,0.3573327,0.01504326,0.000366676,0.02178874,0.00002128067,0.00643188,0.002252699,0.0000409871,0.2533972],"study_design_scores_gemma":[0.1504999,0.01220191,0.6929088,0.04433241,0.08257061,0.0003761142,0.0006541184,0.00002286379,0.002981132,0.001152649,0.007039135,0.005260331],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5435055,0.452509,0.00006512145,0.00003840872,0.0002109168,0.001539438,0.002094338,0.000009927341,0.00002724417],"genre_scores_gemma":[0.5241296,0.4739032,0.0000975714,0.00001589745,0.000002778692,0.0002402815,0.001563578,0.00001542905,0.00003168934],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3943777,"threshold_uncertainty_score":0.9998955,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01473489632815889,"score_gpt":0.2480171576489363,"score_spread":0.2332822613207774,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}