{"id":"W2611067946","doi":"10.2142/biophys.49.s110_1","title":"2P-024 Molecular interactions of CD28 cytoplasmic domains with Grb2 and Gads using their SH3-deficient mutants(Protein:Structure & Function,The 47th Annual Meeting of the Biophysical Society of Japan)","year":2009,"lang":"en","type":"article","venue":"Seibutsu Butsuri","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Mutant; SH3 domain; GRB2; Cytoplasm; Function (biology); Cell biology; Chemistry; Signal transducing adaptor protein; Biology; Biophysics; Genetics; Proto-oncogene tyrosine-protein kinase Src; Signal transduction; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002029645,0.0005088918,0.0002813879,0.0002140769,0.0003693468,0.0003245228,0.000518639,0.0003174942,0.002742067],"category_scores_gemma":[0.0001449627,0.0002155,0.0003431572,0.0002261004,0.0003463107,0.000237527,0.0003867235,0.0009048907,0.0006578499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006317605,"about_ca_system_score_gemma":0.0003395829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00141592,"about_ca_topic_score_gemma":0.00200189,"domain_scores_codex":[0.9998314,0.00003177056,0.0000122895,0.00003085728,0.00004117478,0.00005251954],"domain_scores_gemma":[0.9999195,0.0000191999,0.00001075641,0.00001220984,0.000007241741,0.00003109403],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003732399,0.00008275949,0.0003247122,0.0000376284,0.00001812815,0.0002117039,0.00002757678,0.0001096495,0.9971626,0.0005617189,0.0002338426,0.0008562185],"study_design_scores_gemma":[0.0001321299,0.0001469841,0.004468136,0.000008796292,0.00002594629,0.0005302095,0.00006038956,0.002679605,0.9871597,0.0001232215,0.004655858,0.000009119461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951901,0.0006050665,0.001261057,0.0003082483,0.0000661372,0.00002131527,0.0003361662,0.00002899385,0.00218294],"genre_scores_gemma":[0.9918153,0.0003232306,0.001742056,0.0001095219,0.00001914661,0.00003650835,0.00132226,0.00003003215,0.004601954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002742067,"threshold_uncertainty_score":0.009173095,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008124324630005859,"score_gpt":0.2442863092171783,"score_spread":0.2361619845871724,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}