{"id":"W2611067946","doi":"10.2142/biophys.49.s110_1","title":"2P-024 Molecular interactions of CD28 cytoplasmic domains with Grb2 and Gads using their SH3-deficient mutants(Protein:Structure & Function,The 47th Annual Meeting of the Biophysical Society of Japan)","year":2009,"lang":"en","type":"article","venue":"Seibutsu Butsuri","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Mutant; SH3 domain; GRB2; Cytoplasm; Function (biology); Cell biology; Chemistry; Signal transducing adaptor protein; Biology; Biophysics; Genetics; Proto-oncogene tyrosine-protein kinase Src; Signal transduction; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002183052,0.0001968465,0.0002352942,0.0000431275,0.000179763,0.00001755536,0.0002311124,0.0001238151,0.00001618248],"category_scores_gemma":[0.00005626565,0.0001168055,0.0001878144,0.0003520888,0.0003776697,0.00001165613,0.0001149175,0.000232481,4.695262e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002154822,"about_ca_system_score_gemma":0.0001333391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007487176,"about_ca_topic_score_gemma":0.00004360226,"domain_scores_codex":[0.998652,0.000117407,0.0003248558,0.0003055825,0.000348856,0.0002512773],"domain_scores_gemma":[0.9987941,0.00002468074,0.0002594446,0.0005027386,0.0003628963,0.00005608974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001896534,0.00008447655,0.000923763,0.00004708546,0.0001032836,2.623081e-7,0.0004301596,0.001013803,0.9964243,0.0001810852,0.00009970879,0.000502421],"study_design_scores_gemma":[0.0005780685,0.000370846,0.004498763,0.0001158156,0.00005090046,0.00004179225,0.0009377964,0.0008339619,0.9898129,0.0002146513,0.002387534,0.0001570168],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958767,0.0001765758,0.00269154,0.000395943,0.00005395313,0.0004147519,0.0002041305,0.000007022237,0.0001793497],"genre_scores_gemma":[0.9987546,0.00001531101,0.0008574363,0.0001019266,0.00006262572,0.000005499095,0.00002979897,0.00001728765,0.0001555041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006611445,"threshold_uncertainty_score":0.476319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008124324630005859,"score_gpt":0.2442863092171783,"score_spread":0.2361619845871724,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}