{"id":"W2611093582","doi":"10.1038/s41598-017-01589-4","title":"Identification of Tp0751 (Pallilysin) as a Treponema pallidum Vascular Adhesin by Heterologous Expression in the Lyme disease Spirochete","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Syphilis Diagnosis and Treatment","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria; University of Toronto","funders":"Institute of Musculoskeletal Health and Arthritis; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Toronto; Canada Research Chairs; National Institutes of Health; Deutscher Akademischer Austauschdienst","keywords":"Bacterial adhesin; Borrelia burgdorferi; Treponema; Microbiology; Pathogen; Biology; Doxycycline; Lyme disease; Syphilis; Virology; Immunology; Virulence; Antibiotics; Antibody; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001397544,0.0002247112,0.0001885249,0.0001131501,0.00009175349,0.0003025476,0.0002059526,0.0003563622,0.0005179649],"category_scores_gemma":[0.0001436725,0.000110303,0.0002448567,0.0001249111,0.000194907,0.0001179068,0.0002336312,0.0004933009,0.0002949799],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002338036,"about_ca_system_score_gemma":0.000132393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005162605,"about_ca_topic_score_gemma":0.0005213219,"domain_scores_codex":[0.9998841,0.0000225909,0.00001590512,0.00001867034,0.0000323817,0.00002632722],"domain_scores_gemma":[0.999911,0.00002524831,0.00002399323,0.0000129803,0.000009275038,0.00001757577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002826974,0.00001379281,0.0000891141,0.000007839083,0.000001622143,0.00002459537,0.000006241672,0.00004903793,0.9994556,0.00003939392,0.000008765653,0.0002756694],"study_design_scores_gemma":[0.00001636858,0.0003185766,0.004335406,0.00000623739,0.00001439927,0.0003129067,0.00002892475,0.001951082,0.9916016,0.00002786796,0.001381795,0.000004869791],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996996,0.0002449633,0.002072419,0.00005643959,0.00001432407,0.00001711616,0.0001852098,0.00002429602,0.0003892468],"genre_scores_gemma":[0.9948817,0.0002454983,0.002990206,0.00004228605,0.000006358719,0.00002074206,0.0006157768,0.0000222674,0.001175099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005179649,"threshold_uncertainty_score":0.001732767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02125688897735131,"score_gpt":0.2981909151308619,"score_spread":0.2769340261535106,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}