{"id":"W2611211782","doi":"10.1016/j.tibs.2017.04.001","title":"The Relationship between Alternative Splicing and Proteomic Complexity","year":2017,"lang":"en","type":"letter","venue":"Trends in Biochemical Sciences","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":200,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Computational biology; RNA splicing; Alternative splicing; Biology; Bioinformatics; Genetics; Gene; Exon; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002570754,0.0003601165,0.0005652781,0.0005901814,0.0009203982,0.002119168,0.0008583823,0.007275616,0.003259887],"category_scores_gemma":[0.01091228,0.0002886593,0.000388864,0.0005198246,0.004003859,0.003221916,0.001341235,0.01094831,0.001965676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001337534,"about_ca_system_score_gemma":0.000434731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003619417,"about_ca_topic_score_gemma":0.0005673757,"domain_scores_codex":[0.9988977,0.0002249436,0.0001134399,0.0002403506,0.0004034527,0.0001200748],"domain_scores_gemma":[0.9927086,0.005029494,0.0004397925,0.0005387396,0.0007952934,0.0004881489],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009826411,0.0001226684,0.007778807,0.000384119,0.000107745,0.01239503,0.0005318378,0.0004828956,0.01450423,0.07837839,0.6887267,0.1956049],"study_design_scores_gemma":[0.0002386588,0.0001891122,0.00978673,0.0001814689,0.00007211778,0.01987012,0.0005127793,0.003701769,0.009645283,0.3236466,0.6320286,0.0001268298],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.008890818,0.009983549,0.002642138,0.9571525,0.01600607,0.00001402069,0.0001293112,0.0001361444,0.005045532],"genre_scores_gemma":[0.2233625,0.02468589,0.00556163,0.5361254,0.1940677,0.0001593077,0.0002870404,0.0001311605,0.01561925],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.007275616,"threshold_uncertainty_score":0.01359558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.140654012496897,"score_gpt":0.39201328120956,"score_spread":0.2513592687126631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}