{"id":"W2611361256","doi":"10.25011/cim.v31i4.4788","title":"THE TRANSCRIPTION FACTOR Y-BOX BINDING PROTEIN-1 (YB-1) INDUCES EXPRESSION OF THE PIK3CA ONCOGENE LEADING TO INCREASED INVASION OFBASAL-LIKE BREAST CARCINOMA CELLS","year":2008,"lang":"en","type":"article","venue":"Clinical and investigative medicine","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chromatin immunoprecipitation; Cancer research; Transcription factor; Promoter; Biology; Oncogene; PI3K/AKT/mTOR pathway; Molecular biology; Cancer; Gene expression; Cell cycle; Genetics; Gene; Apoptosis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001106531,0.0003175933,0.0002099603,0.0001957029,0.0001311622,0.000198392,0.0001433989,0.0001804401,0.002000886],"category_scores_gemma":[0.00007819995,0.0001325724,0.0002092014,0.0001975906,0.0001762169,0.00008467972,0.0002398725,0.0004873798,0.0004870793],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003219076,"about_ca_system_score_gemma":0.0001896033,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006954289,"about_ca_topic_score_gemma":0.001180152,"domain_scores_codex":[0.9998934,0.000009851065,0.000006152844,0.00002546895,0.00003305036,0.00003201347],"domain_scores_gemma":[0.9999342,0.00001060355,0.00002360347,0.000006131422,0.000006249922,0.00001922411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007052635,0.00001896356,0.0002263364,0.00003566264,0.000004454764,0.00001790985,0.000004829167,0.0000134735,0.998874,0.0000196323,0.000077007,0.0006373039],"study_design_scores_gemma":[0.00004068326,0.000350382,0.02492849,0.00001189507,0.00002620946,0.0002575723,0.00003358247,0.0008112655,0.9692459,0.00004483878,0.004244626,0.00000463677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902937,0.004147039,0.002251429,0.0002071126,0.00007609415,0.00003231038,0.001143246,0.0002306037,0.001618334],"genre_scores_gemma":[0.9916014,0.001499206,0.001710117,0.0001078253,0.00001808615,0.00004639172,0.002127831,0.00002799651,0.002861092],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002000886,"threshold_uncertainty_score":0.006693661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1056524705965405,"score_gpt":0.3157915982544343,"score_spread":0.2101391276578938,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}