{"id":"W2611427209","doi":"10.14740/wjon1019w","title":"The Era of Multigene Panels Comes? The Clinical Utility of Oncotype DX and MammaPrint","year":2017,"lang":"en","type":"review","venue":"World Journal of Oncology","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Guideline; Clinical Practice; Stage (stratigraphy); Oncology; Breast cancer; Internal medicine; Medical physics; Gynecology; Cancer; Pathology; Family medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003331543,0.0007955695,0.001777834,0.003215848,0.0003546444,0.002143601,0.001465758,0.002237204,0.003705731],"category_scores_gemma":[0.005506035,0.0004097637,0.0009492374,0.002910973,0.001135117,0.003968052,0.001355416,0.004334592,0.002406207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001157846,"about_ca_system_score_gemma":0.002005667,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001263974,"about_ca_topic_score_gemma":0.002045295,"domain_scores_codex":[0.999129,0.0002321414,0.0001243718,0.0001543679,0.00029787,0.00006224788],"domain_scores_gemma":[0.9958456,0.002543308,0.0002769521,0.0001266668,0.0009939189,0.0002135869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008537831,0.00003339485,0.0005296855,0.01000996,0.000125161,0.0003505237,0.0001075791,0.0002292923,0.0006370961,0.009023511,0.06071504,0.9181533],"study_design_scores_gemma":[0.00001238164,0.0000550889,0.0005943202,0.004845571,0.0001090993,0.001689605,0.0001066202,0.00007478384,0.0003106739,0.004300012,0.9878721,0.00002970778],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006991388,0.9961742,0.0002246504,0.002317047,0.0005275517,0.000003260232,0.00002599158,0.00001066657,0.0006469181],"genre_scores_gemma":[0.0007162828,0.9959984,0.0003937336,0.00159226,0.0008290125,0.000007186597,0.00005090235,0.000006370896,0.0004058198],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003705731,"threshold_uncertainty_score":0.01761907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1286053019431654,"score_gpt":0.4486719543814642,"score_spread":0.3200666524382988,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}