{"id":"W2611709607","doi":"10.3390/biology6020028","title":"Developmental Control of NRAMP1 (SLC11A1) Expression in Professional Phagocytes","year":2017,"lang":"en","type":"article","venue":"Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"RIKEN; National Institutes of Health","keywords":"Biology; CTCF; Myelopoiesis; Enhancer; Transcription factor; Epigenetics; Locus (genetics); Locus control region; Genetics; Regulation of gene expression; Cell biology; Haematopoiesis; Gene; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001485094,0.0001011844,0.0001606901,0.0002748068,0.0001531695,0.0003308595,0.0001445758,0.0002002728,0.0009367392],"category_scores_gemma":[0.0002183376,0.0001587102,0.0001751337,0.000156459,0.0002093421,0.0001561094,0.0002928762,0.0003141692,0.000376828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003713603,"about_ca_system_score_gemma":0.0002870451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001206421,"about_ca_topic_score_gemma":0.001745376,"domain_scores_codex":[0.999749,0.0000306481,0.00001916624,0.0001117219,0.00004078041,0.00004867371],"domain_scores_gemma":[0.9997545,0.00005132247,0.00005997127,0.0000204061,0.00005468034,0.00005918594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006695597,0.000004631519,0.002000898,0.00001629967,0.000001845772,0.00006923063,0.00004841196,0.00002381638,0.9964536,0.00009648513,0.00002500187,0.001192585],"study_design_scores_gemma":[0.00001862274,0.000231584,0.3367854,0.00002787158,0.00003024104,0.0008371488,0.0003143475,0.001836658,0.6530043,0.0002456252,0.006644274,0.00002391538],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933006,0.001102605,0.002999141,0.00005622572,0.00001240182,0.00002457316,0.0008574989,0.00005399708,0.001592939],"genre_scores_gemma":[0.9933428,0.0004232213,0.001886973,0.00004931971,0.000006254614,0.00003715023,0.0008300279,0.00003321305,0.003390905],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001206421,"threshold_uncertainty_score":0.003133714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01603388610015943,"score_gpt":0.3099014051392325,"score_spread":0.2938675190390731,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}