{"id":"W2611709607","doi":"10.3390/biology6020028","title":"Developmental Control of NRAMP1 (SLC11A1) Expression in Professional Phagocytes","year":2017,"lang":"en","type":"article","venue":"Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"RIKEN; National Institutes of Health","keywords":"Biology; CTCF; Myelopoiesis; Enhancer; Transcription factor; Epigenetics; Locus (genetics); Locus control region; Genetics; Regulation of gene expression; Cell biology; Haematopoiesis; Gene; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001858284,0.00008009929,0.0001259476,0.00003030209,0.00007963559,0.000005867848,0.0001877841,0.0001714469,0.00002379785],"category_scores_gemma":[0.0001747108,0.00006591019,0.00003396681,0.00001174665,0.0001065787,0.00000256519,0.0001083022,0.0000471955,0.000003721723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007386734,"about_ca_system_score_gemma":0.00006834519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001936467,"about_ca_topic_score_gemma":0.00003671328,"domain_scores_codex":[0.9993805,0.00006307009,0.0001839054,0.0001918167,0.0000422201,0.0001385321],"domain_scores_gemma":[0.9996012,0.00001609283,0.0001449233,0.0001674777,0.0000406944,0.0000295668],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007282399,0.00003943285,0.1878207,0.00000447704,0.000006479371,4.909364e-7,0.00001694938,0.000003007401,0.8085671,0.00007654879,0.00003937768,0.003352664],"study_design_scores_gemma":[0.000865109,0.0001070698,0.1857443,0.00001381584,0.000001976893,6.827553e-7,0.0000166989,0.0000182168,0.8034642,0.0003073751,0.009382585,0.00007797711],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964467,0.0009547952,0.001128594,0.00007048649,0.0002691042,0.0001228158,0.000017545,0.000002401853,0.000987597],"genre_scores_gemma":[0.9982576,0.0001167206,0.001146872,0.00003211347,0.00009003031,0.00001741269,0.00005552216,0.000006638977,0.0002770635],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009343207,"threshold_uncertainty_score":0.268774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01603388610015943,"score_gpt":0.3099014051392325,"score_spread":0.2938675190390731,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}