{"id":"W2611809642","doi":"10.1080/13543784.2017.1324847","title":"The neurogenic compound, NSI-189 phosphate: a novel multi-domain treatment capable of pro-cognitive and antidepressant effects","year":2017,"lang":"en","type":"review","venue":"Expert Opinion on Investigational Drugs","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network; Brain and Cognition Discovery Foundation","funders":"","keywords":"Neurogenesis; Antidepressant; Neuroscience; Cognition; Subventricular zone; Psychology; Neural stem cell; Major depressive disorder; Hippocampus; Stem cell; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001863258,0.0003525867,0.0004021119,0.0002442505,0.0001253509,0.0004623937,0.0003917214,0.0006667967,0.005356923],"category_scores_gemma":[0.0001686465,0.00008841186,0.0002891482,0.0001768864,0.0002175359,0.0003249212,0.000255303,0.0009540815,0.001670098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002911632,"about_ca_system_score_gemma":0.0003187559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004120924,"about_ca_topic_score_gemma":0.001450134,"domain_scores_codex":[0.9999272,0.0000132727,0.00000702091,0.00001621566,0.00002595369,0.00001033207],"domain_scores_gemma":[0.9999537,0.000008467598,0.00001607001,0.000001652998,0.00001374955,0.000006283158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001890505,0.0003121626,0.0006484956,0.0143211,0.0001929698,0.001236749,0.0001182527,0.0008709796,0.1432117,0.009529474,0.0678446,0.759823],"study_design_scores_gemma":[0.0009851197,0.003354342,0.002910197,0.001768166,0.0003733705,0.003695749,0.000116846,0.001209598,0.0520046,0.003222761,0.930304,0.0000552581],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04638151,0.8766081,0.01068758,0.0119129,0.003642433,0.0005857334,0.002647031,0.0003686858,0.04716612],"genre_scores_gemma":[0.1898641,0.7578403,0.006239711,0.007939426,0.00182604,0.0004193143,0.002888057,0.00004138223,0.0329418],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005356923,"threshold_uncertainty_score":0.01792073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1842359574083909,"score_gpt":0.3839717961617744,"score_spread":0.1997358387533835,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}