{"id":"W2612017015","doi":"10.1021/acssynbio.7b00076","title":"Autonomous Cell Migration to CSF1 Sources <i>via</i> a Synthetic Protein-Based System","year":2017,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society Research Institute","keywords":"Vesicular stomatitis virus; RHOA; Cell biology; HEK 293 cells; Cancer research; Microvesicles; Biology; Receptor; Chemistry; Immunology; Signal transduction; Virus; Biochemistry; microRNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001686799,0.0002886945,0.0001795644,0.0001208335,0.0001663962,0.0003107174,0.0002952703,0.0003000903,0.0007895977],"category_scores_gemma":[0.0001249055,0.00011285,0.0001931947,0.00007891806,0.0002129864,0.0001725518,0.000249936,0.000364169,0.0004767083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003157787,"about_ca_system_score_gemma":0.0001844587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003707399,"about_ca_topic_score_gemma":0.000406046,"domain_scores_codex":[0.9998859,0.00002276593,0.00001085317,0.00003278697,0.00002429771,0.00002332758],"domain_scores_gemma":[0.9999211,0.00001377338,0.00002253746,0.00001469848,0.00001083994,0.00001709492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002198483,0.000005852864,0.00002699933,0.00001654024,0.000001002284,0.00001335605,0.000009434119,0.00008349336,0.9988742,0.0002221325,0.00003396528,0.0006909865],"study_design_scores_gemma":[0.00000584002,0.00006253753,0.0001442076,0.000002369908,0.000002967398,0.00005893067,0.000006925235,0.001451893,0.9957046,0.00002700552,0.002530063,0.000002643667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9464133,0.0005985638,0.04840718,0.0002023724,0.00009353959,0.00009906687,0.000295655,0.0003652602,0.003525056],"genre_scores_gemma":[0.9574813,0.0003831715,0.03816329,0.00007483443,0.00001447236,0.00007926956,0.000493106,0.00005486226,0.003255656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007895977,"threshold_uncertainty_score":0.002641499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00994563891459755,"score_gpt":0.213777532542179,"score_spread":0.2038318936275815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}