{"id":"W2612017015","doi":"10.1021/acssynbio.7b00076","title":"Autonomous Cell Migration to CSF1 Sources <i>via</i> a Synthetic Protein-Based System","year":2017,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society Research Institute","keywords":"Vesicular stomatitis virus; RHOA; Cell biology; HEK 293 cells; Cancer research; Microvesicles; Biology; Receptor; Chemistry; Immunology; Signal transduction; Virus; Biochemistry; microRNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005125236,0.0005149836,0.000771711,0.0002435198,0.001212889,0.00008031576,0.001359176,0.00096253,0.0002816207],"category_scores_gemma":[0.0001956181,0.0004301851,0.0002164066,0.00009003141,0.0008469853,0.00007817527,0.0003294691,0.0004884875,0.005094793],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001168978,"about_ca_system_score_gemma":0.0001603714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001125416,"about_ca_topic_score_gemma":0.0002178516,"domain_scores_codex":[0.9967362,0.0005929564,0.0006419851,0.0009703841,0.00004822043,0.001010229],"domain_scores_gemma":[0.9971817,0.0002589301,0.0005410577,0.00180451,0.000131114,0.00008264777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001942957,0.0002464805,0.0005861382,0.00007652484,0.00009483646,0.00001429462,0.0002109703,0.00002351909,0.991116,0.001385046,0.0002805444,0.00577135],"study_design_scores_gemma":[0.001200401,0.0007920679,0.0001401926,0.0001190981,0.0001038141,0.0001403746,0.000179826,0.00007847662,0.9133902,0.0001848267,0.08314443,0.0005262666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846455,0.001617852,0.00258037,0.003277892,0.001817395,0.001124679,0.00006870156,0.0003811216,0.004486492],"genre_scores_gemma":[0.9951777,0.00001293144,0.0003041436,0.0003330096,0.00008348544,0.0003568958,0.00007517697,0.00005675331,0.003599902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08286389,"threshold_uncertainty_score":0.999815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00994563891459755,"score_gpt":0.213777532542179,"score_spread":0.2038318936275815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}