{"id":"W2612204637","doi":"10.1080/21645515.2017.1314874","title":"A new therapeutic potential for cancers: One CAR with 2 different engines!","year":2017,"lang":"en","type":"letter","venue":"Human Vaccines & Immunotherapeutics","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research","funders":"","keywords":"Chimeric antigen receptor; Antigen; Immune system; NK-92; Immunotherapy; Cancer immunotherapy; MHC class I; Cytotoxic T cell; Biology; Immunology; Antigen-presenting cell; Cancer research; Major histocompatibility complex; T cell; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001358177,0.001212231,0.001266951,0.001255078,0.0007264017,0.003050476,0.001272465,0.004083692,0.01005759],"category_scores_gemma":[0.0008363803,0.0005115433,0.001744894,0.0004487994,0.001775885,0.006275529,0.002401459,0.005090493,0.003804237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001235309,"about_ca_system_score_gemma":0.0008386368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006119413,"about_ca_topic_score_gemma":0.0007117419,"domain_scores_codex":[0.9991893,0.0001778021,0.00002924063,0.0001812479,0.0002281207,0.0001943601],"domain_scores_gemma":[0.9996963,0.00008590422,0.00002535614,0.00003417095,0.00006287279,0.00009543589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001183442,0.000893902,0.001433287,0.002505515,0.0002638416,0.001386537,0.0005834883,0.001617316,0.120219,0.2076795,0.08036244,0.5818716],"study_design_scores_gemma":[0.0003081225,0.002502553,0.0007603194,0.0006241335,0.0002347665,0.004813717,0.0002994174,0.002018967,0.03793941,0.046895,0.9033846,0.0002190925],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"editorial","genre_scores_codex":[0.04528504,0.6128803,0.1223791,0.1282533,0.01338343,0.0006349671,0.0005587697,0.001882458,0.07474265],"genre_scores_gemma":[0.3699513,0.2814797,0.1174494,0.09034374,0.008709822,0.001894268,0.001025056,0.0005509302,0.1285957],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.01005759,"threshold_uncertainty_score":0.03364605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05411203792392574,"score_gpt":0.3252653102509973,"score_spread":0.2711532723270715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}