{"id":"W2612297280","doi":"10.1016/j.celrep.2017.04.046","title":"Epithelial Histone Deacetylase 3 Instructs Intestinal Immunity by Coordinating Local Lymphocyte Activation","year":2017,"lang":"en","type":"article","venue":"Cell Reports","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Crohn's and Colitis Foundation; Presbyterian Historical Society; Burroughs Wellcome Fund","keywords":"HDAC3; Intraepithelial lymphocyte; Biology; Histone deacetylase; Immunology; Histone; Cell biology; Immunity; Innate lymphoid cell; Innate immune system; Immune system; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003450839,0.0002087415,0.0002390247,0.0000736215,0.001153323,0.000072665,0.0001902504,0.0002292355,0.0008146123],"category_scores_gemma":[0.0005703318,0.0002071122,0.00009674172,0.00004213441,0.000324238,0.0004682427,0.0001463707,0.0004428466,0.0002563114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000314162,"about_ca_system_score_gemma":0.0001366377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001328076,"about_ca_topic_score_gemma":0.00001031713,"domain_scores_codex":[0.9987121,0.0001165918,0.0004781455,0.0003393852,0.00005640933,0.0002973999],"domain_scores_gemma":[0.998093,0.00007042476,0.0009003781,0.0007227393,0.0001800196,0.00003339988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001667131,0.0001307328,0.0004757661,0.00001725995,0.0000293332,0.00003545488,0.0001258811,0.000006157222,0.9507192,0.00002090375,0.01789395,0.03037867],"study_design_scores_gemma":[0.0008369393,0.0001081032,0.002061192,0.00004605575,0.00002211935,0.000716702,0.0001970658,0.00003018692,0.8419059,0.00003026467,0.1538534,0.0001920617],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9635272,0.0003947279,0.003510909,0.0001091363,0.00758605,0.0001778255,0.000001472315,0.0001126037,0.02458009],"genre_scores_gemma":[0.9535994,0.00002404607,0.00006845225,0.0001033501,0.00004818109,0.0000150433,0.0002168227,0.00002288304,0.04590183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1359595,"threshold_uncertainty_score":0.8919433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01117844393339444,"score_gpt":0.2476349972276626,"score_spread":0.2364565532942681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}