{"id":"W2612297280","doi":"10.1016/j.celrep.2017.04.046","title":"Epithelial Histone Deacetylase 3 Instructs Intestinal Immunity by Coordinating Local Lymphocyte Activation","year":2017,"lang":"en","type":"article","venue":"Cell Reports","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Crohn's and Colitis Foundation; Presbyterian Historical Society; Burroughs Wellcome Fund","keywords":"HDAC3; Intraepithelial lymphocyte; Biology; Histone deacetylase; Immunology; Histone; Cell biology; Immunity; Innate lymphoid cell; Innate immune system; Immune system; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001964872,0.0003175984,0.0002711807,0.0001865855,0.0002188349,0.0007102783,0.0003045503,0.0003066357,0.003100133],"category_scores_gemma":[0.0001616813,0.000174688,0.0003411467,0.0001509121,0.0003994702,0.0003157899,0.0003975936,0.0007326503,0.0007058504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006036754,"about_ca_system_score_gemma":0.000420632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001012394,"about_ca_topic_score_gemma":0.003437945,"domain_scores_codex":[0.9997997,0.0000242917,0.00001162354,0.00004529924,0.00004038969,0.00007864845],"domain_scores_gemma":[0.9998887,0.000007301056,0.00002655765,0.00001882268,0.00001566186,0.00004303145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003134354,0.00002140333,0.00143887,0.00005128422,0.00001285604,0.00006942846,0.00001986243,0.00006766419,0.9925537,0.0004750614,0.0002554489,0.004721079],"study_design_scores_gemma":[0.00005947307,0.0002970133,0.0286571,0.00001446181,0.00005263768,0.0002958585,0.0001636187,0.001001086,0.9591134,0.0004115006,0.009921275,0.00001260462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9670354,0.006178191,0.01254531,0.0009506787,0.00051919,0.00005473966,0.001169641,0.000634848,0.01091199],"genre_scores_gemma":[0.9941109,0.0007071547,0.001504113,0.0001124815,0.00002962387,0.00001003368,0.0003404219,0.00004504016,0.003140192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003100133,"threshold_uncertainty_score":0.01037097,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01117844393339444,"score_gpt":0.2476349972276626,"score_spread":0.2364565532942681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}