{"id":"W2612496622","doi":"10.21873/anticanres.11554","title":"Delayed Progression of Lung Metastases Following Delivery of a Prodrug-activating Enzyme","year":2017,"lang":"en","type":"article","venue":"Anticancer Research","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Cancer Institute; Breast Cancer Society of Canada","keywords":"Prodrug; Cytosine deaminase; Chemotherapy; Medicine; Cancer research; Lung cancer; Cancer; Pharmacology; Pathology; Chemistry; Internal medicine; Biochemistry; Genetic enhancement","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001215208,0.0001986401,0.0001566005,0.0001114833,0.00007523343,0.0001395589,0.0001491904,0.0002282521,0.001225839],"category_scores_gemma":[0.0001238481,0.00007867536,0.0001102233,0.00006292178,0.0001535117,0.0001577443,0.00008683809,0.0005365277,0.0001926043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003318204,"about_ca_system_score_gemma":0.000252281,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009455434,"about_ca_topic_score_gemma":0.001267322,"domain_scores_codex":[0.9999415,0.000006794453,0.00000308732,0.00001682872,0.00001615402,0.00001557849],"domain_scores_gemma":[0.9999001,0.00003271529,0.00002329745,0.000008411297,0.00001418399,0.00002136753],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001394273,0.0000527292,0.0001987567,0.00003010353,0.000003461558,0.00006028074,0.00000843927,0.0001275297,0.9974062,0.00005990177,0.00004914976,0.001864044],"study_design_scores_gemma":[0.00002320127,0.0008388932,0.001780537,0.000002781174,0.000007357919,0.0002182198,0.00000630702,0.001201877,0.9953335,0.00002854842,0.0005564013,0.000002235367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912701,0.001470254,0.005663577,0.00008599777,0.00002405664,0.00006063801,0.0001595463,0.00009304182,0.001172843],"genre_scores_gemma":[0.9958739,0.0003558832,0.001928576,0.00003298991,0.000004790206,0.00003152509,0.0001418254,0.00001039399,0.00162017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001225839,"threshold_uncertainty_score":0.0041008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06373069076704924,"score_gpt":0.4623242769717718,"score_spread":0.3985935862047225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}