{"id":"W2612601964","doi":"10.1161/hyp.62.suppl_1.a300","title":"Abstract 300: Targeted Deletion of Matrix Metalloproteinase 2 Prevents Angiotensin II-Induced Endothelial Dysfunction and Vascular Remodeling, Oxidative Stress and Inflammation","year":2013,"lang":"en","type":"article","venue":"Hypertension","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Endocrinology; Internal medicine; Angiotensin II; Oxidative stress; NADPH oxidase; Medicine; MMP2; Inflammation; Endothelial dysfunction; Chemistry; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001761353,0.0009777793,0.0006178283,0.0003282815,0.0001652259,0.0003893417,0.0004737821,0.0006313812,0.005178925],"category_scores_gemma":[0.0001381107,0.0003308204,0.0003988181,0.0001868542,0.00037541,0.0003700834,0.0002503209,0.001033987,0.001908341],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003166943,"about_ca_system_score_gemma":0.0003247772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003910525,"about_ca_topic_score_gemma":0.0004037896,"domain_scores_codex":[0.9997827,0.00002305059,0.00002719618,0.00004415963,0.00006262497,0.0000603147],"domain_scores_gemma":[0.999757,0.00002016701,0.00008055173,0.00001709766,0.00002206139,0.0001031608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007092458,0.00016852,0.00007115757,0.0000631187,0.000009297702,0.000088104,0.000007894304,0.00004232362,0.9974566,0.00006642262,0.0001981089,0.001119189],"study_design_scores_gemma":[0.0003822363,0.002138825,0.003849718,0.00002616476,0.00005899943,0.0006848549,0.0000286651,0.0009376457,0.988526,0.0001193977,0.003235516,0.00001194857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807436,0.002433719,0.007955636,0.000490936,0.0002738578,0.0001701221,0.003143443,0.0007254292,0.004063326],"genre_scores_gemma":[0.9639279,0.002293642,0.007769102,0.0003200428,0.0001389461,0.0003208885,0.004607362,0.0002236306,0.02039858],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005178925,"threshold_uncertainty_score":0.01732522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01294296078498917,"score_gpt":0.2056757065270946,"score_spread":0.1927327457421055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}