{"id":"W2612733314","doi":"10.1002/eji.201646795","title":"Regulation of immune cell signaling by SHIP1: A phosphatase, scaffold protein, and potential therapeutic target","year":2017,"lang":"en","type":"review","venue":"European Journal of Immunology","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Institute of Infection and Immunity; Canadian Institutes of Health Research","keywords":"Biology; Immune system; Cell biology; Scaffold; Phosphatase; Scaffold protein; Signal transduction; Cell; Immunology; Biochemistry; Phosphorylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004682451,0.0008917812,0.0009598786,0.001643725,0.0002398769,0.0009143127,0.0006731848,0.0009910804,0.002754848],"category_scores_gemma":[0.000412006,0.0002363575,0.000301597,0.001581916,0.0004709968,0.001340671,0.0007572706,0.00189425,0.002394616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005898128,"about_ca_system_score_gemma":0.0007958345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003930111,"about_ca_topic_score_gemma":0.0008581775,"domain_scores_codex":[0.9998972,0.00001429537,0.00001522365,0.00002082632,0.00003784967,0.00001443588],"domain_scores_gemma":[0.999843,0.00005020664,0.00002518015,0.000005754021,0.00004721923,0.00002866172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009427451,0.00008088612,0.0001656168,0.00788348,0.00005780626,0.0002899816,0.00004129033,0.0004070909,0.004503779,0.005363693,0.03446325,0.946649],"study_design_scores_gemma":[0.00002059417,0.0000882831,0.0004759122,0.0009747249,0.00005743683,0.001203351,0.00003246422,0.0001235282,0.001094734,0.001703403,0.99421,0.00001570315],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001694359,0.997888,0.0002092362,0.0003753175,0.0003320563,0.000005143149,0.00001924168,0.00001139267,0.0009901907],"genre_scores_gemma":[0.0008387587,0.997528,0.0002175792,0.000228033,0.0002791123,0.000009012441,0.00003624851,0.000002392607,0.0008608418],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002754848,"threshold_uncertainty_score":0.009215832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02068935066640992,"score_gpt":0.2636312890490392,"score_spread":0.2429419383826293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}