{"id":"W2612746336","doi":"10.21037/jtd.2017.04.16","title":"RASSF1A methylation, YAP1 activation and metastasis: a new role for an old foe in lung cancer","year":2017,"lang":"en","type":"letter","venue":"Journal of Thoracic Disease","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Medicine; YAP1; Lung cancer; Methylation; Metastasis; Cancer research; Cancer; Oncology; Bioinformatics; Internal medicine; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003488763,0.0002262425,0.000318565,0.0002076539,0.00007830761,0.0001051304,0.0002294257,0.000384831,0.00001323918],"category_scores_gemma":[0.0002157402,0.0002151489,0.0001943172,0.00005778847,0.00003206674,0.00005103607,0.00004097559,0.0003544411,1.97294e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001094176,"about_ca_system_score_gemma":0.0007021423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007659377,"about_ca_topic_score_gemma":0.00005597871,"domain_scores_codex":[0.9986929,0.0001216747,0.0004208948,0.0003090964,0.0002530623,0.0002023327],"domain_scores_gemma":[0.9982017,0.00002267615,0.0009698572,0.0003621604,0.0002570376,0.0001865447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003139041,0.0001140665,0.002862056,0.00111535,0.000975824,0.00003524962,0.0001507438,0.004245938,0.06464173,0.000004940617,0.8187894,0.1039256],"study_design_scores_gemma":[0.003824324,0.00076468,0.01862918,0.002448799,0.003701517,0.0000525994,0.00006554599,0.003509002,0.07331313,0.003078569,0.8891133,0.001499334],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6256794,0.05849265,0.02406001,0.2867563,0.001901178,0.002394422,0.0006050131,0.00002070473,0.00009035673],"genre_scores_gemma":[0.8752298,0.004727101,0.005616024,0.06130698,0.0398433,0.0003043841,0.003066075,0.0004154024,0.009490982],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2495504,"threshold_uncertainty_score":0.8773516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01947413782606929,"score_gpt":0.3563237924355229,"score_spread":0.3368496546094537,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}