{"id":"W2612777803","doi":"10.1093/annonc/mdx091.013","title":"Afatinib (A) vs gefitinib (G) in patients with EGFR mutation-positive (EGFRm+) NSCLC: Updated OS data from the phase IIb trial LUX-Lung 7 (LL7)","year":2017,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Afatinib; Internal medicine; Gefitinib; Discontinuation; Clinical endpoint; Lung cancer; Gastroenterology; Oncology; Clinical trial; Cancer; Epidermal growth factor receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003014442,0.001053844,0.002683603,0.0005443274,0.0003233218,0.001608171,0.0009234032,0.001180624,0.003327908],"category_scores_gemma":[0.002544246,0.0003507289,0.003699264,0.0008496447,0.000646879,0.002029493,0.0004745147,0.003142525,0.0008031249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0012719,"about_ca_system_score_gemma":0.0009765159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001414258,"about_ca_topic_score_gemma":0.006055128,"domain_scores_codex":[0.998922,0.0005457073,0.0001100679,0.0001482126,0.0001046784,0.0001693795],"domain_scores_gemma":[0.9985747,0.0004749951,0.000448028,0.0001051053,0.00009113706,0.0003059589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7231069,0.00231659,0.01764267,0.002826765,0.01078997,0.0001578549,0.0002176211,0.004526319,0.007561292,0.0006780627,0.01630332,0.2138726],"study_design_scores_gemma":[0.6864135,0.1571629,0.1006136,0.0008476942,0.0184308,0.0009389717,0.0004518126,0.004803848,0.003135131,0.003727846,0.02322753,0.000246465],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9241115,0.05288538,0.0008843425,0.003888139,0.0007249709,0.0005345838,0.007932943,0.0002286803,0.008809325],"genre_scores_gemma":[0.9723836,0.0107887,0.001183738,0.002950979,0.0004678015,0.0004042759,0.009295982,0.00007335519,0.002451566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003327908,"threshold_uncertainty_score":0.0159421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08899710198320918,"score_gpt":0.4670936908508817,"score_spread":0.3780965888676725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}