{"id":"W2613352189","doi":"10.3390/genes8050138","title":"DNA Methylation Dynamics and Cocaine in the Brain: Progress and Prospects","year":2017,"lang":"en","type":"review","venue":"Genes","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institute on Drug Abuse","keywords":"DNA methylation; Epigenetics; Methyltransferase; Methylation; Biology; Epigenomics; Mechanism (biology); Genetics; DNA; Computational biology; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004987179,0.0001995418,0.0003586433,0.00005102431,0.0001081179,0.0000990185,0.0001659209,0.0002541252,6.150767e-7],"category_scores_gemma":[0.00009269672,0.000136011,0.00006008802,0.00004770987,0.0001147887,0.000002825434,0.0001068003,0.00009215171,6.708536e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009716976,"about_ca_system_score_gemma":0.0000562055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005485083,"about_ca_topic_score_gemma":0.0001372113,"domain_scores_codex":[0.9990751,0.0001411009,0.000219725,0.0003330642,0.00008963763,0.0001413319],"domain_scores_gemma":[0.9993198,0.00003673652,0.0002079035,0.0003727495,0.00003243258,0.00003041028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000002571629,0.00001123533,0.000342936,0.001107927,0.00002360262,0.000002256288,0.00002678721,2.919026e-7,0.0001222818,0.0001495883,0.00001500181,0.9981955],"study_design_scores_gemma":[0.0001755389,0.0001244365,0.000998119,0.0004389919,0.00009982778,0.00001575102,0.00001326806,0.00004048299,0.0002914011,0.0002683714,0.9972926,0.0002412111],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004679351,0.994215,0.00006312878,0.000148975,0.00006980982,0.0006235822,0.00002179614,0.000003356819,0.0001749993],"genre_scores_gemma":[0.00202122,0.996865,0.0002178139,0.00001925332,0.0001962178,0.00008571359,0.0003641422,0.00002254172,0.0002080864],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9979543,"threshold_uncertainty_score":0.5546367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04415491556218284,"score_gpt":0.3581233454395638,"score_spread":0.3139684298773809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}