{"id":"W2613352189","doi":"10.3390/genes8050138","title":"DNA Methylation Dynamics and Cocaine in the Brain: Progress and Prospects","year":2017,"lang":"en","type":"review","venue":"Genes","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institute on Drug Abuse","keywords":"DNA methylation; Epigenetics; Methyltransferase; Methylation; Biology; Epigenomics; Mechanism (biology); Genetics; DNA; Computational biology; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000479544,0.0005756143,0.0008670805,0.001311578,0.0002607164,0.0009036762,0.000597687,0.001010323,0.003851595],"category_scores_gemma":[0.0005967993,0.0002076903,0.000257117,0.001590121,0.0004733715,0.001460206,0.0008660647,0.00136053,0.001794269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005952051,"about_ca_system_score_gemma":0.001135592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008394495,"about_ca_topic_score_gemma":0.001653894,"domain_scores_codex":[0.9999024,0.00001609521,0.00001540698,0.00002268843,0.00003199203,0.00001148446],"domain_scores_gemma":[0.9997401,0.0001168562,0.00003346723,0.000008619508,0.0000660047,0.00003492959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007490203,0.0000381527,0.0002567202,0.01027071,0.00004748484,0.0001844405,0.00007253511,0.0004439792,0.002299494,0.007849105,0.02813086,0.9503317],"study_design_scores_gemma":[0.000005568446,0.00004195917,0.0006485355,0.002159596,0.00005314348,0.00081565,0.00005736155,0.00008351877,0.0004059185,0.003910275,0.9918035,0.00001497999],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008342068,0.9986417,0.0001071453,0.0003690427,0.0001670433,0.000001366973,0.00001083496,0.0000047897,0.0006147237],"genre_scores_gemma":[0.0004354425,0.9987405,0.0001000247,0.0001265588,0.0001761153,0.000002040625,0.00001352536,0.000001166313,0.0004045923],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003851595,"threshold_uncertainty_score":0.01288486,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04415491556218284,"score_gpt":0.3581233454395638,"score_spread":0.3139684298773809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}