{"id":"W2613444241","doi":"10.1016/j.chom.2017.08.010","title":"The Landscape of Type VI Secretion across Human Gut Microbiomes Reveals Its Role in Community Composition","year":2017,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":184,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute of General Medical Sciences; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; National Center for Complementary and Integrative Health; Simons Foundation; Life Sciences Research Foundation; Burroughs Wellcome Fund; Howard Hughes Medical Institute","keywords":"Biology; Microbiome; Effector; Metagenomics; Type VI secretion system; Bacteroides fragilis; Competition (biology); Bacteroides; Secretion; Phenotype; Gene; Microbiology; Evolutionary biology; Genetics; Ecology; Bacteria; Cell biology; Virulence","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005105758,0.0001435512,0.0001802328,0.00002551801,0.001057988,0.00007913145,0.0005350347,0.0001872866,0.00001302515],"category_scores_gemma":[0.00001933778,0.000123664,0.00006838201,0.00004779218,0.0001694496,0.000007586991,0.0003107761,0.000227591,0.00002215021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002152011,"about_ca_system_score_gemma":0.00004484797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002924388,"about_ca_topic_score_gemma":0.0006985117,"domain_scores_codex":[0.9990148,0.0001704655,0.000276163,0.0001882432,0.00004422229,0.000306083],"domain_scores_gemma":[0.9987807,0.00001614853,0.0002672265,0.0007577806,0.0001318481,0.0000463216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006833568,0.0001119951,0.007812571,0.00008245035,0.00001025256,6.914535e-7,0.0003961799,0.000001567606,0.9896332,0.00001251473,0.001741679,0.0001285495],"study_design_scores_gemma":[0.0007191769,0.0002377178,0.1197816,0.00006922591,0.000008606357,0.000008650136,0.000351439,0.000003406527,0.8692835,0.00002083834,0.009364888,0.0001510003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964224,0.00177179,0.000005088133,0.0001297756,0.0001363734,0.0002296171,0.00009024963,0.000006073569,0.001208668],"genre_scores_gemma":[0.9979193,0.0005181323,0.00004850602,0.0001166994,0.00006474192,0.000004079835,0.0004513449,0.00001876404,0.0008584049],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1203497,"threshold_uncertainty_score":0.8137293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01310184259992938,"score_gpt":0.300198603860683,"score_spread":0.2870967612607536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}