{"id":"W2613444241","doi":"10.1016/j.chom.2017.08.010","title":"The Landscape of Type VI Secretion across Human Gut Microbiomes Reveals Its Role in Community Composition","year":2017,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":184,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute of General Medical Sciences; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; National Center for Complementary and Integrative Health; Simons Foundation; Life Sciences Research Foundation; Burroughs Wellcome Fund; Howard Hughes Medical Institute","keywords":"Biology; Microbiome; Effector; Metagenomics; Type VI secretion system; Bacteroides fragilis; Competition (biology); Bacteroides; Secretion; Phenotype; Gene; Microbiology; Evolutionary biology; Genetics; Ecology; Bacteria; Cell biology; Virulence","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002035758,0.0001316024,0.0002871348,0.0005044268,0.0002019566,0.0009966689,0.0001192025,0.0002895907,0.001412254],"category_scores_gemma":[0.0004402068,0.000151305,0.000223269,0.0004800361,0.000284586,0.0003465096,0.0003261427,0.0002735328,0.0003027078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001483624,"about_ca_system_score_gemma":0.0001295317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007779889,"about_ca_topic_score_gemma":0.0008906506,"domain_scores_codex":[0.9998528,0.00003602172,0.000007763069,0.0000510242,0.00002447068,0.00002796644],"domain_scores_gemma":[0.9998047,0.00004277553,0.00004986021,0.00002258254,0.00004006691,0.00004013709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001374902,0.00003063797,0.1843285,0.0001140403,0.0001588141,0.0000969357,0.0004015268,0.0003643625,0.7935299,0.0005538951,0.0003042702,0.01874223],"study_design_scores_gemma":[0.00001446294,0.0002479105,0.9494374,0.00003334132,0.00008407793,0.0005152255,0.001072034,0.003155636,0.04192317,0.001310606,0.002180089,0.00002599801],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995928,0.001813903,0.0009208394,0.0001214749,0.00001256959,0.000002689767,0.0005013272,0.00001780694,0.0006813529],"genre_scores_gemma":[0.9982285,0.0005168564,0.0004847798,0.0000551029,0.00001494001,0.000003774491,0.0002726529,0.00001193948,0.0004113645],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001412254,"threshold_uncertainty_score":0.004724443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01310184259992938,"score_gpt":0.300198603860683,"score_spread":0.2870967612607536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}