{"id":"W2613572458","doi":"10.1172/jci92450","title":"Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":227,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Medical Research Council; NYU Langone Medical Center; Baker Heart and Diabetes Institute; Diabetes Australia; York University; University of Alabama; National Institutes of Health; Diabetes Australia Research Trust; University of Alabama at Birmingham; National Health and Medical Research Council","keywords":"Thrombocytosis; Platelet; Internal medicine; Thrombopoietin; Endocrinology; Medicine; Diabetes mellitus; Platelet activation; CD36; Receptor; Immunology; Biology; Cell biology; Stem cell","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001109584,0.0002772374,0.0001766713,0.0002063566,0.0000937224,0.0001685324,0.0000905823,0.0001762573,0.000807741],"category_scores_gemma":[0.00009549465,0.00009072234,0.0002549527,0.0001016853,0.0001302997,0.00009452704,0.0001617651,0.0004771973,0.0001328235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000133554,"about_ca_system_score_gemma":0.00008542972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003624052,"about_ca_topic_score_gemma":0.0004199022,"domain_scores_codex":[0.9999421,0.00001428329,0.000006493142,0.00001142621,0.00001200534,0.00001371665],"domain_scores_gemma":[0.9999191,0.000008645718,0.00002986446,0.00000700964,0.000007377937,0.00002800062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008080853,0.00008934287,0.002133243,0.00004224265,0.00002353441,0.0002579564,0.00001426667,0.00005799326,0.9928356,0.00008449468,0.00008766389,0.003565546],"study_design_scores_gemma":[0.0003170022,0.002220826,0.1525994,0.00002715833,0.0001539705,0.002141814,0.0001065997,0.002447825,0.8345659,0.0003217053,0.005080277,0.00001756786],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964674,0.001998845,0.0007514298,0.00007375915,0.00002276567,0.00001083492,0.00007491218,0.00003289524,0.00056725],"genre_scores_gemma":[0.9975417,0.0009293711,0.0006822132,0.00005765712,0.00001345127,0.00001361325,0.00009313337,0.000005235948,0.0006637275],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000807741,"threshold_uncertainty_score":0.002702117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0755240779911421,"score_gpt":0.362002348624719,"score_spread":0.2864782706335769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}