{"id":"W2614024007","doi":"10.1161/atvb.33.suppl_1.a30","title":"Abstract 30: Leveraging the Innate Immunity Pathway for Transdifferentiation of Fibroblasts to Endothelial Cells","year":2013,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cooke Aquaculture (Canada)","funders":"","keywords":"Transdifferentiation; Reprogramming; Cell biology; Biology; Induced pluripotent stem cell; Chromatin; Innate immune system; Endothelial stem cell; TLR3; Immunology; Stem cell; Cell; Embryonic stem cell; Toll-like receptor; Immune system; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002588915,0.0003759778,0.0001933366,0.0001914037,0.0001473363,0.0003422867,0.0002134978,0.0003358733,0.004126496],"category_scores_gemma":[0.00008321791,0.00009841046,0.0003770859,0.0001325473,0.0001547226,0.0002382187,0.0003670153,0.0005649148,0.001602193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001870847,"about_ca_system_score_gemma":0.0002132994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002976413,"about_ca_topic_score_gemma":0.0004649599,"domain_scores_codex":[0.9998423,0.00002242647,0.00002188483,0.00003897778,0.00004677142,0.00002760011],"domain_scores_gemma":[0.9999112,0.00001355594,0.00001979168,0.00001468074,0.00001493336,0.00002588055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003314317,0.00002665298,0.00008123419,0.00005283057,0.000002995685,0.00004634689,0.000007838004,0.00002902733,0.9976268,0.0001309471,0.00007537766,0.001886758],"study_design_scores_gemma":[0.00001604809,0.0002222754,0.001449101,0.00001137239,0.0000144,0.0002594668,0.00001205444,0.0003950221,0.9894503,0.0001017838,0.00806342,0.000004810222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.93622,0.008122073,0.03585119,0.0006960358,0.0005339278,0.0003305027,0.002194382,0.0005198833,0.01553202],"genre_scores_gemma":[0.9614597,0.003353609,0.01975265,0.0002876671,0.0000618982,0.0001608757,0.001664968,0.00006919409,0.01318946],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004126496,"threshold_uncertainty_score":0.0138045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02863474519092913,"score_gpt":0.2655062196055585,"score_spread":0.2368714744146294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}