{"id":"W2614394261","doi":"10.6004/jnccn.2017.0070","title":"Use of Biomarkers and Multigene Assays in Breast Cancer","year":2017,"lang":"en","type":"article","venue":"Journal of the National Comprehensive Cancer Network","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Amgen (Canada)","funders":"","keywords":"Medicine; Breast cancer; Oncology; Estrogen receptor; Internal medicine; Endocrine system; Adjuvant therapy; Adjuvant; Chemotherapy; Estrogen; Cancer; Bioinformatics; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00921761,0.0005925834,0.0007693589,0.004566437,0.000390454,0.001759335,0.0007087931,0.001131626,0.0009697455],"category_scores_gemma":[0.01199292,0.0003096124,0.0004253227,0.003927542,0.0007674986,0.001090649,0.001096591,0.0009715368,0.0005067803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007429237,"about_ca_system_score_gemma":0.0007223072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008182037,"about_ca_topic_score_gemma":0.0008955342,"domain_scores_codex":[0.9931289,0.004358305,0.0004471618,0.0005998084,0.00131403,0.0001518279],"domain_scores_gemma":[0.9919941,0.003438137,0.002406442,0.0007313553,0.00107865,0.0003513071],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001648665,0.0002869108,0.5034657,0.001160807,0.0005443488,0.0006063371,0.0002174145,0.002191525,0.0139056,0.008326553,0.006230224,0.4614158],"study_design_scores_gemma":[0.0001648605,0.004083245,0.7327754,0.00176277,0.001181566,0.009601949,0.0007119619,0.01388354,0.03773779,0.04282937,0.1549827,0.0002848321],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2754225,0.5895553,0.08341645,0.01226492,0.003432089,0.0005773712,0.003573181,0.0008157767,0.03094241],"genre_scores_gemma":[0.8662159,0.04763781,0.07633968,0.003363759,0.001568754,0.000556422,0.0009391651,0.00006754721,0.003310979],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00921761,"threshold_uncertainty_score":0.04874796,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05250035401155284,"score_gpt":0.3270827985108631,"score_spread":0.2745824444993103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}