{"id":"W2614699794","doi":"10.3389/fmolb.2017.00030","title":"Tetrabutylphosphonium Bromide Reduces Size and Polydispersity Index of Tat2:siRNA Nano-Complexes for Triticale RNAi","year":2017,"lang":"en","type":"article","venue":"Frontiers in Molecular Biosciences","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge; Agriculture and Agri-Food Canada","funders":"","keywords":"Nucleic acid; Chemistry; Dispersity; Biophysics; RNA; Ethidium bromide; Small interfering RNA; RNA interference; Biochemistry; DNA; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002681869,0.0001591628,0.0002459524,0.00007473469,0.0002406045,0.0000934796,0.000668932,0.0001377923,0.000003560651],"category_scores_gemma":[0.0004569586,0.000148593,0.0001081233,0.00006956568,0.00121137,0.00002123317,0.0001745025,0.00006302247,3.038514e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001073764,"about_ca_system_score_gemma":0.00008656883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001301093,"about_ca_topic_score_gemma":0.0000520625,"domain_scores_codex":[0.9987783,0.00003138528,0.0002290201,0.0004780263,0.0001671859,0.0003160749],"domain_scores_gemma":[0.9992891,0.00001660533,0.0001466905,0.0003819599,0.00007736374,0.00008831327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000123752,0.00005051987,0.04071544,0.00002063496,0.00002503125,0.000003241032,0.00004944292,0.000004584987,0.9561078,0.00006100809,0.0009926595,0.001845875],"study_design_scores_gemma":[0.0006087907,0.000356907,0.02610498,0.00003961107,0.00001496228,0.000004459354,0.0005505306,0.0001276323,0.9703497,0.0009053426,0.0007298175,0.0002072438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868904,0.002075102,0.009620545,0.0003091592,0.0005559542,0.0002222568,0.00005034231,0.000004296184,0.0002719459],"genre_scores_gemma":[0.9902055,0.0004132201,0.008926849,0.0001349667,0.00004073263,0.00001346262,0.000006859731,0.000009177609,0.0002492797],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01461046,"threshold_uncertainty_score":0.6059445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007828133479746438,"score_gpt":0.2550301321299744,"score_spread":0.247201998650228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}