{"id":"W2614887256","doi":"10.3233/jad-170188","title":"The Mechanisms of Action of Curcumin in Alzheimer’s Disease","year":2017,"lang":"en","type":"review","venue":"Journal of Alzheimer s Disease","topic":"Curcumin's Biomedical Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":300,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Curcumin; Pharmacology; Disease; Bioavailability; Medicine; Hyperphosphorylation; In vivo; Drug; Neuroscience; Chemistry; Biology; Internal medicine; Biochemistry; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000612227,0.0003272377,0.0009573812,0.0001765513,0.00009809703,0.00002746973,0.0009940002,0.0002246261,0.00002699136],"category_scores_gemma":[0.0003841589,0.0002208566,0.001012554,0.0001606229,0.0003613279,0.00001304907,0.0002136045,0.0003106417,0.000005848972],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002055496,"about_ca_system_score_gemma":0.001365174,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009785388,"about_ca_topic_score_gemma":0.000005351234,"domain_scores_codex":[0.9974125,0.0001993551,0.001361044,0.0002940292,0.0004851716,0.0002478904],"domain_scores_gemma":[0.9954202,0.00007564818,0.002687955,0.001023574,0.0002750867,0.0005175172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003324087,0.0006745992,0.00003769386,0.001219752,0.00220433,0.00004074842,0.00001104489,0.000003041513,0.0007684357,0.0004760461,0.003345306,0.9908866],"study_design_scores_gemma":[0.0004422756,0.0001430413,0.000373417,0.002158883,0.007918025,0.00001878181,0.00001670855,0.000005823157,0.001308885,0.00101732,0.9863189,0.0002779222],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001115558,0.9981622,0.0003255338,0.0002478368,0.0003330325,0.0005316415,0.0002424203,0.000002252677,0.00004354951],"genre_scores_gemma":[0.01748835,0.9817143,0.0001392967,0.00002394616,0.000359891,0.00005874919,0.0001323823,0.0000474947,0.0000355632],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9906087,"threshold_uncertainty_score":0.9006272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1087595333606593,"score_gpt":0.404315780771769,"score_spread":0.2955562474111096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}