{"id":"W2614912162","doi":"10.1080/10428194.2017.1318439","title":"Use of minimal residual disease assessment in the treatment of chronic lymphocytic leukemia","year":2017,"lang":"en","type":"review","venue":"Leukemia & lymphoma/Leukemia and lymphoma","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; Roche (Canada); University of Calgary; McGill University; Jewish General Hospital; Queen Elizabeth II Health Sciences Centre; Fluidigm (Canada); Foothills Medical Centre","funders":"","keywords":"Medicine; Minimal residual disease; Oncology; Clinical trial; Chronic lymphocytic leukemia; Clinical endpoint; Surrogate endpoint; Internal medicine; Complete remission; Leukemia; Intensive care medicine; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00185667,0.0005661738,0.002103985,0.003179863,0.0002273586,0.001095429,0.001113457,0.001055472,0.001914924],"category_scores_gemma":[0.002427156,0.0002735641,0.001051507,0.00239686,0.0007590627,0.00133936,0.0007013876,0.001930472,0.0006434427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007826027,"about_ca_system_score_gemma":0.001251772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00147189,"about_ca_topic_score_gemma":0.002466931,"domain_scores_codex":[0.9992377,0.0002455794,0.000175523,0.00008853952,0.000220276,0.00003239931],"domain_scores_gemma":[0.9987835,0.0008346739,0.0001648937,0.00002263419,0.0001620238,0.00003226392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001139452,0.0000449658,0.000293665,0.03415717,0.000258368,0.0001144371,0.00006756136,0.0003176469,0.0004951159,0.00314603,0.007851215,0.9531399],"study_design_scores_gemma":[0.0001109823,0.0003008452,0.002882378,0.03004473,0.0009634634,0.002297895,0.0001538029,0.0002507543,0.0007813771,0.004239346,0.9579138,0.00006062227],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000622986,0.9994264,0.00005510167,0.0001133491,0.00004683126,0.000004907347,0.000007870374,0.000001581641,0.0002817419],"genre_scores_gemma":[0.001079829,0.9983932,0.0001848749,0.0001593847,0.00006295093,0.000007958293,0.00001723405,9.855885e-7,0.00009360073],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003179863,"threshold_uncertainty_score":0.00981915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1113431687691861,"score_gpt":0.3888589566978046,"score_spread":0.2775157879286185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}