{"id":"W2615014982","doi":"10.1177/0885328217708458","title":"Nanoformulated water-soluble paclitaxel to enhance drug efficacy and reduce hemolysis side effect","year":2017,"lang":"en","type":"article","venue":"Journal of Biomaterials Applications","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; University of Alberta","funders":"","keywords":"Paclitaxel; Hemolysis; Drug; Nanocarriers; Pharmacology; In vivo; Chemotherapy; Poloxamer; Medicine; Chemistry; Surgery; Biology; Internal medicine; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001759671,0.0002323714,0.0005391525,0.0001567571,0.0007022707,0.000701709,0.0007576894,0.0000804607,0.0001264255],"category_scores_gemma":[0.0002042952,0.0001653205,0.00009391712,0.0001064008,0.0001709885,0.0005846933,0.0002647649,0.00004736589,0.0004745737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007955662,"about_ca_system_score_gemma":0.00005812494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001165642,"about_ca_topic_score_gemma":0.000008449456,"domain_scores_codex":[0.9978536,0.0001533025,0.0008639548,0.0003516586,0.0003426327,0.0004348602],"domain_scores_gemma":[0.9976365,0.0001437505,0.000730896,0.0008959007,0.0002669964,0.0003259597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000255927,0.0001261247,0.00004097789,0.00004496643,0.00002607463,0.00001058081,0.0002010931,0.00002333776,0.996015,0.00002630646,0.0008373308,0.00239224],"study_design_scores_gemma":[0.000710645,0.0002025037,0.0008275732,0.00008710886,0.00009914354,0.00007039678,0.00001914698,0.000009953122,0.9943746,0.0002177275,0.003171789,0.0002094241],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951698,0.0001218337,0.0004555748,0.002875583,0.0005533724,0.0006732971,0.00004280204,0.00005190361,0.00005584026],"genre_scores_gemma":[0.9960697,0.00002930486,0.003207718,0.00008415883,0.000306747,0.0000955357,0.000005528226,0.00002969013,0.0001716768],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002791424,"threshold_uncertainty_score":0.6766595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009920136121388286,"score_gpt":0.2987578829494988,"score_spread":0.2888377468281105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}