{"id":"W2615489086","doi":"10.1097/01.tp.0000520305.95347.22","title":"Reprogramming and Recapitulating T Cells in the Immature Immune Environment of the Neonate to Induce Transplant Tolerance","year":2017,"lang":"en","type":"article","venue":"Transplantation","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; Alberta Biodiversity Monitoring Institute; Northern Alberta Institute of Technology; University of Alberta","funders":"","keywords":"CD154; Biology; CD8; Spleen; Immunology; Immune tolerance; Immune system; Cytotoxic T cell; CD40; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002099546,0.0002873468,0.0002352165,0.0002225023,0.0001411414,0.0003026437,0.0002620811,0.0003432801,0.001988537],"category_scores_gemma":[0.000129108,0.0001278741,0.0002255569,0.00009965093,0.0002020745,0.0001544632,0.0002935068,0.000763857,0.0008669664],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000176117,"about_ca_system_score_gemma":0.0002070499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000211292,"about_ca_topic_score_gemma":0.0004419376,"domain_scores_codex":[0.9998343,0.00002505291,0.00002759652,0.00003605583,0.00004536479,0.00003155875],"domain_scores_gemma":[0.9998839,0.00001558517,0.0000299998,0.00002149027,0.00001334047,0.00003566229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005784968,0.0000182328,0.0002370645,0.00003306846,0.000002126374,0.0001198651,0.00003205982,0.00003960827,0.9980879,0.0000939051,0.00004600221,0.001232172],"study_design_scores_gemma":[0.00002080032,0.0006358105,0.005083851,0.00003003063,0.00002194608,0.001015005,0.00007048,0.0004185385,0.9854688,0.00007697208,0.007151771,0.000006040602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838837,0.001448721,0.00953755,0.0001124082,0.00008789013,0.0002103506,0.001327794,0.0001968945,0.003194777],"genre_scores_gemma":[0.9785112,0.001652814,0.007856335,0.0001634351,0.00002002751,0.0003743938,0.001572237,0.0001062052,0.009743304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001988537,"threshold_uncertainty_score":0.006652296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02207427108721115,"score_gpt":0.2919425535102369,"score_spread":0.2698682824230257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}