{"id":"W2615493985","doi":"10.1016/j.bbamcr.2017.05.013","title":"New intracellular activities of matrix metalloproteinases shine in the moonlight","year":2017,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":181,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Matrix metalloproteinase; Proteases; Cell biology; Extracellular matrix; Biology; Intracellular; Extracellular; Proteome; Subcellular localization; Signal transduction; Bioinformatics; Biochemistry; Enzyme; Cytoplasm","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002035185,0.0008588051,0.001591351,0.0005236971,0.0002543405,0.0002924042,0.003123021,0.0008867712,0.00003530414],"category_scores_gemma":[0.0002774117,0.0006296178,0.001153031,0.0005814238,0.0004345166,0.00002798167,0.001176412,0.00145508,0.00004277667],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006871585,"about_ca_system_score_gemma":0.001655899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002402397,"about_ca_topic_score_gemma":0.00001718498,"domain_scores_codex":[0.9935385,0.001935887,0.0008993218,0.001282456,0.001327124,0.001016698],"domain_scores_gemma":[0.9958184,0.0001544469,0.000697519,0.002920926,0.000171947,0.0002367588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000081136,0.0003624156,2.487273e-8,0.003242508,0.0002461761,0.0001020292,0.00007659692,3.829001e-7,0.9631618,0.0003975697,0.001587599,0.03074181],"study_design_scores_gemma":[0.0002914738,0.0005040955,2.965578e-7,0.001218175,0.00019178,0.00001288839,0.00004264048,0.000002098205,0.7054946,0.0002216936,0.2915618,0.0004584727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02477196,0.9694227,0.0001360954,0.0002682925,0.0001378032,0.002979998,0.0001741426,0.00001840189,0.002090611],"genre_scores_gemma":[0.07274982,0.9228206,0.0007894686,0.00004438591,0.0005292338,0.0004121331,0.0007474457,0.0001825589,0.001724352],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.2899742,"threshold_uncertainty_score":0.9996155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09061666534119359,"score_gpt":0.4119173614998217,"score_spread":0.3213006961586281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}