{"id":"W2615835252","doi":"10.1093/hmg/ddp050","title":"Pax2 gene dosage influences cystogenesis in autosomal dominant polycystic kidney disease","year":2009,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Children's Hospital","funders":"","keywords":"Biology; Polycystic kidney disease; Autosomal dominant polycystic kidney disease; Gene; Gene dosage; Genetics; Polycystic kidney; Kidney; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003002088,0.0002231975,0.000349183,0.0007126409,0.0001890403,0.0004343462,0.0002023599,0.0003845175,0.002782469],"category_scores_gemma":[0.0005876906,0.0002957636,0.0001802879,0.0003686239,0.0005218352,0.0002326584,0.0004248026,0.0003397138,0.0004494872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002027925,"about_ca_system_score_gemma":0.0001650041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004592615,"about_ca_topic_score_gemma":0.0008782842,"domain_scores_codex":[0.9996789,0.0001147334,0.000037191,0.00005250883,0.00008304249,0.0000336501],"domain_scores_gemma":[0.9996545,0.0001529647,0.00008435758,0.0000309063,0.0000196599,0.00005754822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008699769,0.00002588614,0.00811108,0.0000471403,0.00003116598,0.001590098,0.0001117475,0.0003374155,0.9817522,0.0007333304,0.0004029484,0.005987004],"study_design_scores_gemma":[0.0002661642,0.0004261955,0.3466635,0.00006028998,0.000253254,0.0191592,0.0007011561,0.005137795,0.6179246,0.002346847,0.006956522,0.0001044788],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962831,0.0008128168,0.0008859062,0.0001619368,0.00003291605,0.000005501008,0.000231314,0.00005092156,0.001535588],"genre_scores_gemma":[0.9977755,0.0005230622,0.0004990842,0.00003751297,0.00001193323,0.000008255688,0.0001100389,0.0000537696,0.0009809526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002782469,"threshold_uncertainty_score":0.009308279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007857946732323243,"score_gpt":0.2540044427379137,"score_spread":0.2461464960055905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}