{"id":"W2615970934","doi":"10.4049/jimmunol.1602121","title":"RIG-I–like Receptor Triggering by Dengue Virus Drives Dendritic Cell Immune Activation and TH1 Differentiation","year":2017,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Leids Universitair Medisch Centrum; University of Oxford","keywords":"Biology; Dengue virus; Immune system; Immunology; Acquired immune system; Cytokine; Chemokine; Innate immune system; Dendritic cell; MDA5; TLR7; Cell biology; Dengue fever; Toll-like receptor; RNA interference; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001684613,0.0002616577,0.0001937399,0.0001504721,0.0001572699,0.0003223225,0.0001591174,0.0002794924,0.001463382],"category_scores_gemma":[0.0000862333,0.0001313741,0.0003482153,0.0001184272,0.0001762566,0.0001681165,0.000255441,0.0006383887,0.000538887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000303065,"about_ca_system_score_gemma":0.0001858143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002460404,"about_ca_topic_score_gemma":0.0003073827,"domain_scores_codex":[0.9997645,0.00003783237,0.00002700511,0.00004880582,0.00003535784,0.0000864578],"domain_scores_gemma":[0.999931,0.00001046777,0.00001780317,0.000009765974,0.00001050559,0.00002056555],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001168395,0.00003118629,0.0003580164,0.00005249641,0.000003392969,0.00003728447,0.00001497042,0.00004975766,0.9983745,0.0001326585,0.00006951739,0.0007592711],"study_design_scores_gemma":[0.00004912305,0.0003444384,0.004296197,0.00001781989,0.00002373891,0.0002399892,0.00008413197,0.002186792,0.9866871,0.0001205244,0.005942365,0.000007763981],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883455,0.002012408,0.00482844,0.0001819066,0.00009528457,0.00008220744,0.001085053,0.00009358804,0.003275582],"genre_scores_gemma":[0.9943877,0.0006135166,0.002311832,0.0001113561,0.00001514825,0.00004183548,0.0006752117,0.0000114862,0.001831747],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001463382,"threshold_uncertainty_score":0.004895508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007130630471772533,"score_gpt":0.2408623623016303,"score_spread":0.2337317318298577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}