{"id":"W2615991916","doi":"10.1093/biolre/iox045","title":"Ovary-specific depletion of the nuclear receptor Nr5a2 compromises expansion of the cumulus oophorus but not fertilization by intracytoplasmic sperm injection†","year":2017,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal","funders":"","keywords":"Biology; Liver receptor homolog-1; Granulosa cell; Endocrinology; Nuclear receptor; Internal medicine; Equine chorionic gonadotropin; Amphiregulin; Cumulus oophorus; Ovary; Epiregulin; Oocyte; Ovarian follicle; Receptor; Cell biology; Ovulation; Embryo; Transcription factor; Genetics; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007141177,0.0001548334,0.0003851156,0.00005643678,0.0003692027,0.000004498512,0.0002870935,0.0002701959,0.00006406535],"category_scores_gemma":[0.001387404,0.00009459338,0.0001639744,0.0001400851,0.001504171,0.000105358,0.0001345212,0.0002420015,0.000005476919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006522206,"about_ca_system_score_gemma":0.00006444123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002152597,"about_ca_topic_score_gemma":0.000005439751,"domain_scores_codex":[0.9982365,0.0002958307,0.0005332852,0.0006336176,0.0001529905,0.0001477631],"domain_scores_gemma":[0.9967243,0.00003524413,0.0008905975,0.001878021,0.0004447839,0.0000270496],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003316374,0.0001940146,0.09946518,0.00006230622,0.00005119366,6.360578e-8,0.000153146,0.000007143023,0.8858796,0.0001743125,0.0008776613,0.009818955],"study_design_scores_gemma":[0.0003761371,0.0002126927,0.4600602,0.00003988016,0.00002608928,0.00002042363,0.00007718111,0.00001456873,0.5358342,0.0001183098,0.003172674,0.00004767735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935045,0.00117347,0.0001112592,0.001997433,0.002276864,0.0006950769,0.00003047871,0.00002591369,0.0001850092],"genre_scores_gemma":[0.9986433,0.0005193975,0.0002107872,0.00002151067,0.0002774887,0.000009740528,0.00002952625,0.00001430639,0.0002739175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.360595,"threshold_uncertainty_score":0.5542181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0297928771533204,"score_gpt":0.2729189000535005,"score_spread":0.2431260229001801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}