{"id":"W2615991916","doi":"10.1093/biolre/iox045","title":"Ovary-specific depletion of the nuclear receptor Nr5a2 compromises expansion of the cumulus oophorus but not fertilization by intracytoplasmic sperm injection†","year":2017,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal","funders":"","keywords":"Biology; Liver receptor homolog-1; Granulosa cell; Endocrinology; Nuclear receptor; Internal medicine; Equine chorionic gonadotropin; Amphiregulin; Cumulus oophorus; Ovary; Epiregulin; Oocyte; Ovarian follicle; Receptor; Cell biology; Ovulation; Embryo; Transcription factor; Genetics; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003143376,0.0005690817,0.0003571991,0.0005818327,0.0002973761,0.0004080209,0.000470718,0.0005385847,0.003697958],"category_scores_gemma":[0.0001462199,0.0003152977,0.000381017,0.0001959262,0.0004414229,0.0003632005,0.0003818084,0.0008914822,0.0008744959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003898844,"about_ca_system_score_gemma":0.0002610454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008632969,"about_ca_topic_score_gemma":0.00225847,"domain_scores_codex":[0.9995479,0.00004170117,0.00006600756,0.0001254175,0.0001339013,0.00008503609],"domain_scores_gemma":[0.9996657,0.0000393372,0.0001002132,0.00004913574,0.00002062084,0.0001249731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005152262,0.00002178906,0.00006527893,0.0000188103,0.000003001322,0.00003857497,0.00001158244,0.00001375993,0.9993153,0.00009186652,0.00004443811,0.0003242515],"study_design_scores_gemma":[0.00002756396,0.0002129477,0.002538136,0.000005529863,0.00001582094,0.0002439119,0.00002864646,0.0004571508,0.9924367,0.00002714224,0.004001891,0.000004556504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9824774,0.001912834,0.006794069,0.0002618151,0.0001632492,0.000214132,0.002890062,0.0005084024,0.004778071],"genre_scores_gemma":[0.970448,0.001101702,0.006413424,0.0001633663,0.00003326283,0.0002514132,0.002056887,0.0002365984,0.01929522],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003697958,"threshold_uncertainty_score":0.01237088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0297928771533204,"score_gpt":0.2729189000535005,"score_spread":0.2431260229001801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}