{"id":"W2616105943","doi":"10.1038/s41598-017-02380-1","title":"Induction of senescence in primary glioblastoma cells by serum and TGFβ","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Ottawa Hospital Research Institute; Canadian Institutes of Health Research; University of Ottawa","keywords":"Senescence; Biology; CDKN2A; Phenotype; Cancer research; Activator (genetics); Transforming growth factor; Oncogene; Cell cycle; Cell biology; Cell; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002127573,0.0002671133,0.0005841778,0.000358299,0.0002503853,0.0002840566,0.0001512643,0.0001845958,0.001893237],"category_scores_gemma":[0.0001133113,0.0001662232,0.0004971178,0.0003936377,0.0001254112,0.0001014657,0.0002037418,0.0006050533,0.0008235092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003379659,"about_ca_system_score_gemma":0.0002873791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002366463,"about_ca_topic_score_gemma":0.003988202,"domain_scores_codex":[0.9997609,0.00002904823,0.00003659033,0.00004404667,0.00006717865,0.00006212002],"domain_scores_gemma":[0.9998628,0.00002560372,0.00001844026,0.00002443793,0.00003903375,0.00002965583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000206781,0.00007101526,0.0003803015,0.00005852345,0.000007719886,0.0001003185,0.00005989467,0.00004390429,0.9975619,0.00004858334,0.0001537201,0.00130733],"study_design_scores_gemma":[0.00004950419,0.00151777,0.01879747,0.00001993118,0.00002989292,0.000640521,0.00008317919,0.0008052841,0.9711929,0.00006632699,0.006788604,0.000008569024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841599,0.004901844,0.003708572,0.0001483584,0.0001434095,0.0001893374,0.003118188,0.000192213,0.003438177],"genre_scores_gemma":[0.9730142,0.003064348,0.007535808,0.00022785,0.0000457254,0.0004359441,0.007144577,0.00004937056,0.008482248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002366463,"threshold_uncertainty_score":0.00633347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01073484898416951,"score_gpt":0.2476805721162165,"score_spread":0.236945723132047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}