{"id":"W2616437816","doi":"10.1038/onc.2017.110","title":"Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells","year":2017,"lang":"en","type":"article","venue":"Oncogene","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Institute of Genetics; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Research Resources; Brain Tumour Charity; Deutsches Krebsforschungszentrum; Deutsche Forschungsgemeinschaft; National Cancer Institute; Cancer Research UK; American Lebanese Syrian Associated Charities; Vanderbilt University","keywords":"Biology; Embryonic stem cell; Medulloblastoma; Progenitor cell; Cerebellum; Neurogenesis; Cell biology; Neural stem cell; Cancer research; Neuroscience; Stem cell; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002054104,0.0007429693,0.0002917506,0.0007830383,0.0002254378,0.0002993223,0.0003587082,0.0004730142,0.001436073],"category_scores_gemma":[0.00009604717,0.0002252065,0.0004189804,0.0001971801,0.0003665209,0.0002844,0.0003606817,0.0008118292,0.000330456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004889889,"about_ca_system_score_gemma":0.0003101016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009118992,"about_ca_topic_score_gemma":0.002214571,"domain_scores_codex":[0.9997987,0.00002722895,0.00002289324,0.00004472484,0.00007048671,0.00003603805],"domain_scores_gemma":[0.9998804,0.00001304825,0.00004376559,0.00001783206,0.000008266045,0.00003666429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001641718,0.0000884711,0.0005020014,0.00004557738,0.00001168513,0.0003236793,0.00004213933,0.0001340104,0.9963063,0.0005697883,0.0000765693,0.001735677],"study_design_scores_gemma":[0.00008199189,0.001314824,0.00379576,0.00001703906,0.00005862546,0.002466907,0.00005181357,0.001308991,0.9837508,0.0002019311,0.006940594,0.00001075956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859124,0.0008168812,0.01024156,0.0001207889,0.00004863808,0.0002598422,0.0007026061,0.0002640721,0.001633145],"genre_scores_gemma":[0.9860685,0.0009173027,0.006752932,0.00005140116,0.000008854258,0.000224413,0.0008869957,0.0000665466,0.005023084],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001436073,"threshold_uncertainty_score":0.004804194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0377060389208506,"score_gpt":0.2734472010988317,"score_spread":0.2357411621779811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}