{"id":"W2616753020","doi":"10.1016/j.cell.2017.04.037","title":"Antibodies from a Human Survivor Define Sites of Vulnerability for Broad Protection against Ebolaviruses","year":2017,"lang":"en","type":"article","venue":"Cell","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":176,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; Public Health Agency of Canada","funders":"National Institute of Allergy and Infectious Diseases; Defense Threat Reduction Agency; National Institutes of Health; Deutscher Akademischer Austauschdienst; Public Health Agency of Canada","keywords":"Biology; Virology; Ebola virus; Ebolavirus; Monoclonal antibody; Epitope; Antibody; Viral entry; Immune system; Virus; Immunology; Viral replication","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002670598,0.00009419843,0.0002428403,0.00006311532,0.0004536619,0.00004323938,0.00008686264,0.00008379335,0.00008461606],"category_scores_gemma":[0.00023806,0.00007568836,0.000118262,0.00002993233,0.0001641735,0.00009143349,0.00005751679,0.0001479307,0.00001713195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002796664,"about_ca_system_score_gemma":0.00003634052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004885721,"about_ca_topic_score_gemma":0.001508008,"domain_scores_codex":[0.9992693,0.00003319009,0.0001951571,0.0002048059,0.0001368793,0.0001606697],"domain_scores_gemma":[0.9991136,0.00005216372,0.0001184387,0.0004516103,0.000205618,0.00005861843],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001288008,0.0002640554,0.06528126,0.0002164451,0.00002722585,0.000001403916,0.00007814918,0.000001830217,0.9278118,0.00001641059,0.0003898525,0.005782767],"study_design_scores_gemma":[0.001210312,0.0003886018,0.2162162,0.00005563386,0.00002921581,6.5686e-7,0.00004999395,0.0002363468,0.778041,0.0003687985,0.003320537,0.00008265876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906012,0.0001552698,0.0003776744,0.0001493737,0.00008178502,0.0006767172,0.0000788532,0.00003240924,0.007846721],"genre_scores_gemma":[0.9979391,0.00004211804,0.0003398631,0.00002366315,0.0001680861,0.00005829563,0.00005370565,0.00001215685,0.00136309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1509349,"threshold_uncertainty_score":0.7385781,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.108527963529261,"score_gpt":0.3853515032358593,"score_spread":0.2768235397065983,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}