{"id":"W2617250545","doi":"10.1089/ten.tea.2016.0533","title":"Thyroxine Increases Collagen Type II Expression and Accumulation in Scaffold-Free Tissue-Engineered Articular Cartilage","year":2017,"lang":"en","type":"article","venue":"Tissue Engineering Part A","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Toronto Metropolitan University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research; National Institutes of Health; California HIV/AIDS Research Program","keywords":"Glycosaminoglycan; Chemistry; Extracellular matrix; Type II collagen; Cartilage; Aggrecan; Type I collagen; Chondrocyte; Collagen, type I, alpha 1; Tissue engineering; Internal medicine; Endocrinology; Andrology; Anatomy; Biochemistry; Articular cartilage; Biomedical engineering; Osteoarthritis; Biology; Pathology; In vitro; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002193592,0.0004043539,0.0002830621,0.0003372057,0.0001267547,0.0004046159,0.0001650848,0.0002872046,0.0007718744],"category_scores_gemma":[0.0002195984,0.0001670762,0.0003228773,0.0001924378,0.0002215234,0.0002184923,0.000177279,0.0003103669,0.0002287294],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002432999,"about_ca_system_score_gemma":0.00022179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001236833,"about_ca_topic_score_gemma":0.002250528,"domain_scores_codex":[0.9997119,0.00005346659,0.00003396958,0.00004814818,0.0001047652,0.00004771662],"domain_scores_gemma":[0.9996025,0.0000980531,0.0001214154,0.00003290754,0.00005479265,0.00009036684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005759207,0.00001293098,0.00005691828,0.00001798272,0.000002814521,0.00001872198,0.00001218826,0.00001683382,0.9994913,0.00000381777,0.000003714902,0.0003052033],"study_design_scores_gemma":[0.000009043594,0.0007922855,0.003488365,0.000004412577,0.00001672081,0.00009503333,0.00003587788,0.0002791236,0.9947412,0.000008337215,0.0005241039,0.000005471175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968149,0.001387465,0.0009667363,0.00002062829,0.00001827028,0.00001447414,0.0001029962,0.00003425492,0.0006402213],"genre_scores_gemma":[0.9949169,0.00076543,0.002054758,0.00003039764,0.000009550477,0.00002032771,0.0002184968,0.00002162611,0.00196244],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001236833,"threshold_uncertainty_score":0.002582192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02317895128199523,"score_gpt":0.2798630022144492,"score_spread":0.2566840509324539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}