{"id":"W2617261553","doi":"10.1039/c7fd00134g","title":"Quantitative surface-enhanced Raman spectroscopy of single bases in oligodeoxynucleotides","year":2017,"lang":"en","type":"article","venue":"Faraday Discussions","topic":"Gold and Silver Nanoparticles Synthesis and Applications","field":"Materials Science","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Department for Employment and Learning, Northern Ireland","keywords":"Nucleobase; Chemistry; Spectral line; Hydroxylamine; Surface-enhanced Raman spectroscopy; Analytical Chemistry (journal); Raman spectroscopy; Sequence (biology); Oligonucleotide; DNA; Stereochemistry; Chromatography; Optics; Raman scattering; Biochemistry; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000190511,0.0001155142,0.0002445478,0.0000357409,0.0003788685,0.000101615,0.0003900469,0.00003570238,0.0003550844],"category_scores_gemma":[0.000173671,0.00007653654,0.000069567,0.00007479971,0.000225781,0.0002373526,0.00009542155,0.00005342574,0.0001007651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000237022,"about_ca_system_score_gemma":0.000034399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002748642,"about_ca_topic_score_gemma":0.0003761118,"domain_scores_codex":[0.9989902,0.00005855818,0.0002923513,0.0002548471,0.0001540797,0.0002499012],"domain_scores_gemma":[0.9990293,0.00008911388,0.0002034884,0.0005685142,0.00003459699,0.00007497326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001577681,0.000275542,0.001628122,0.000007131231,0.000002461099,0.000001057413,0.0003684607,0.0001050138,0.9891607,0.008056968,0.0001821496,0.0001966621],"study_design_scores_gemma":[0.0002020049,0.0000649002,0.03395595,0.00009149313,0.000009344159,2.89298e-7,0.0006603919,0.0001467493,0.9631462,0.001397101,0.0002093697,0.0001162177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945281,0.00004841128,0.0002198891,0.00126079,0.0001122672,0.0001576471,0.00006450318,0.00002843285,0.003579937],"genre_scores_gemma":[0.9943939,0.00001990919,0.005265541,0.00002052863,0.00001933207,0.00001528278,0.000002791935,0.00001096006,0.0002516955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03232783,"threshold_uncertainty_score":0.3887925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03685875184488784,"score_gpt":0.3036185148222313,"score_spread":0.2667597629773435,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}