{"id":"W2617443522","doi":"10.1038/modpathol.2017.30","title":"Central pathology review with two-stage quality assurance for pathological response after neoadjuvant chemotherapy in the ARTemis Trial","year":2017,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"University of California, San Francisco; University of Warwick; Cancer Research UK; National Institute for Health and Care Research; Sanofi","keywords":"Medicine; Breast cancer; Surgical pathology; Neoadjuvant therapy; Pathological; Biopsy; Chemotherapy; Concordance; Cancer; Axillary lymph nodes; Clinical trial; Oncology; Pathology; Internal medicine; Radiology; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001633144,0.0003358188,0.000599798,0.0000259352,0.0002501907,0.00003393462,0.0005390862,0.0002238083,0.00001614294],"category_scores_gemma":[0.0005771474,0.0002116838,0.0001893653,0.00003534683,0.0004965023,0.000009716997,0.0001200553,0.000186371,0.000003871211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003697095,"about_ca_system_score_gemma":0.0001017499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001742023,"about_ca_topic_score_gemma":0.0003744143,"domain_scores_codex":[0.9970323,0.0009669028,0.0004166929,0.0008131942,0.0001579739,0.0006129327],"domain_scores_gemma":[0.9979881,0.0001670342,0.0003220405,0.001383162,0.00008292234,0.00005671374],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7182656,0.002727622,0.14244,0.0007481512,0.0003767012,0.004854551,0.003949841,0.00009855931,0.06943663,0.0003420187,0.002683108,0.05407726],"study_design_scores_gemma":[0.0713101,0.002947362,0.9063696,0.0002064261,0.0001356,0.0006895444,0.0001151569,0.00003057426,0.00207636,0.0006383666,0.01474638,0.0007345422],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9781414,0.006095268,0.004967891,0.008696482,0.0001979038,0.001499986,0.0002357136,0.00001666069,0.0001487033],"genre_scores_gemma":[0.9895939,0.002137548,0.0011575,0.004883441,0.0002494138,0.001725763,0.00006649477,0.00003276827,0.0001531358],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7639296,"threshold_uncertainty_score":0.8632213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03302755846073274,"score_gpt":0.3489213377323492,"score_spread":0.3158937792716165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}