{"id":"W2617468904","doi":"10.1128/mbio.00603-17","title":"Peptidoglycan Association of Murein Lipoprotein Is Required for KpsD-Dependent Group 2 Capsular Polysaccharide Expression and Serum Resistance in a Uropathogenic <i>Escherichia coli</i> Isolate","year":2017,"lang":"en","type":"article","venue":"mBio","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research; Genentech; Canada Research Chairs; Government of Canada","keywords":"Peptidoglycan; Microbiology; Bacterial outer membrane; Biology; Escherichia coli; Cell envelope; Complement system; Lipoprotein; Mutant; Bacterial cell structure; Bacterial capsule; Bacteria; In vivo; Lysis; Cell wall; Biochemistry; Immunology; Virulence; Cholesterol; Gene; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007200554,0.0001836904,0.0002753539,0.00004233657,0.0002558478,0.0000625562,0.0003191884,0.0002051005,0.000004493692],"category_scores_gemma":[0.0006443038,0.0001843146,0.00008849527,0.00005498509,0.00008721882,0.00001830145,0.0003322679,0.0001340483,0.000001101037],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006594638,"about_ca_system_score_gemma":0.00007199179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002564486,"about_ca_topic_score_gemma":0.002544159,"domain_scores_codex":[0.998486,0.0001119842,0.0003005283,0.0004667532,0.0002485649,0.0003861753],"domain_scores_gemma":[0.9988152,0.00002340782,0.0003713685,0.0005726196,0.0001380549,0.00007932798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003626937,0.00005849453,0.01039859,0.0001039496,0.00004730152,0.000003783518,0.0001944674,7.089596e-7,0.9879848,0.00002806122,0.0005333543,0.0002838129],"study_design_scores_gemma":[0.002390313,0.0003641384,0.07131618,0.0001407062,0.00002902873,7.394651e-7,0.0001048977,0.00009595196,0.9195139,0.000309313,0.005423459,0.0003113196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962582,0.001744382,0.0002424784,0.0006367237,0.00007530707,0.0006693725,0.0001356062,0.000008612245,0.000229348],"genre_scores_gemma":[0.9942702,0.0006249883,0.001997785,0.0001141087,0.0001046308,0.0001807321,0.00001172345,0.00002982617,0.002666007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06847082,"threshold_uncertainty_score":0.7516131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01124758010162074,"score_gpt":0.2620458855063754,"score_spread":0.2507983054047546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}