{"id":"W2617651358","doi":"10.1089/hum.2016.167","title":"Induced Cell Turnover: A Novel Therapeutic Modality for <i>In Situ</i> Tissue Regeneration","year":2017,"lang":"en","type":"review","venue":"Human Gene Therapy","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Homing (biology); Transplantation; Regenerative medicine; Regeneration (biology); Cell biology; Ex vivo; Tissue engineering; Self-healing hydrogels; Biology; Genetic enhancement; Induced pluripotent stem cell; Stem cell; Cancer research; In vivo; Medicine; Chemistry; Embryonic stem cell; Biotechnology; Surgery; Gene; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005835193,0.0007159115,0.002377552,0.0003221527,0.000241983,0.00005616524,0.00032918,0.0005450184,0.00003860868],"category_scores_gemma":[0.00002166134,0.0005216617,0.0004314953,0.0001536401,0.00007698689,0.00005777567,0.00002828563,0.0005961796,0.00001532168],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002323584,"about_ca_system_score_gemma":0.0003124547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003915518,"about_ca_topic_score_gemma":0.00003867984,"domain_scores_codex":[0.9976048,0.0001003537,0.0007862338,0.0007222219,0.0003174354,0.0004689389],"domain_scores_gemma":[0.9980537,0.00007228111,0.0004550358,0.001154277,0.0001007923,0.0001638687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005327331,0.0004207978,0.000001682882,0.004964652,0.0002622855,0.0000282626,0.000288246,0.000008225408,0.2256447,0.0003794832,0.0003540393,0.7675943],"study_design_scores_gemma":[0.004019245,0.0009269079,0.00003015758,0.003097431,0.000389774,0.000081124,0.000005268565,0.0000151374,0.02262167,0.00005121919,0.9682231,0.0005389723],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001367442,0.9913026,0.002780562,0.0001635933,0.0007023641,0.003227349,0.00004246001,0.0000970795,0.0003165485],"genre_scores_gemma":[0.004701986,0.9774895,0.0007242059,0.00007718948,0.00263642,0.0006263914,0.0007624635,0.000204215,0.01277759],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.967869,"threshold_uncertainty_score":0.9997235,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2345444610523304,"score_gpt":0.4208875801227316,"score_spread":0.1863431190704012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}