{"id":"W2618039989","doi":"10.1021/acs.jafc.7b01611","title":"Transport of the Glucosamine-Derived Browning Product Fructosazine (Polyhydroxyalkylpyrazine) Across the Human Intestinal Caco-2 Cell Monolayer: Role of the Hexose Transporters","year":2017,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Biopolymer Synthesis and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Ministry of Agriculture and Forestry; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Caco-2; Hexose; Browning; Chemistry; Biochemistry; Glucosamine; Cell; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000121183,0.000163816,0.0002095224,0.000003547678,0.000433444,0.00002389717,0.0007709331,0.00008546506,0.000003901946],"category_scores_gemma":[0.00001962298,0.00006749212,0.0002763296,0.00004807281,0.0003323432,0.00001062236,0.00008273882,0.0002180833,5.146646e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005536474,"about_ca_system_score_gemma":0.00003402455,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002842209,"about_ca_topic_score_gemma":0.00002872201,"domain_scores_codex":[0.9990799,0.00001521932,0.0004133168,0.0001616115,0.0001739325,0.0001560533],"domain_scores_gemma":[0.998551,0.000008164995,0.0008271502,0.0004257419,0.0001346871,0.00005325288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001793837,0.00007362085,0.008224965,0.00005411249,0.00007192368,2.053881e-7,0.0002738955,0.000008106398,0.9908031,0.000004143278,0.00003090263,0.0004370941],"study_design_scores_gemma":[0.0002609928,0.00005417832,0.2606668,0.00006383008,0.00007100699,0.00009570231,0.0005458654,6.892982e-7,0.7379118,0.00001041282,0.0002422884,0.00007645217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968992,0.001573166,0.000004059635,0.0009531944,0.00004573404,0.000102647,0.00003980946,0.000001770885,0.0003803431],"genre_scores_gemma":[0.9994274,0.00009515928,0.0000363524,0.00001674921,0.0002379531,0.000004244117,0.000006075856,0.00000774414,0.0001682928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2528913,"threshold_uncertainty_score":0.3333745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006786022062655815,"score_gpt":0.2106937153472798,"score_spread":0.203907693284624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}