{"id":"W2618052122","doi":"10.4236/wjv.2017.72002","title":"The Tat Protein Enhances CTL Responses and Therapeutic Immunity of Gag-Specific Exosome-Targeted T Cell-Based Gag/Tat-Texo Vaccine in Transgenic HLA-A2 Mice","year":2017,"lang":"en","type":"article","venue":"World Journal of Vaccines","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"CTL*; Immunogenicity; Virology; CD8; Biology; Group-specific antigen; Epitope; Cellular immunity; Immunology; Cytotoxic T cell; Immune system; Antigen; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002412632,0.0007154506,0.000357061,0.000313308,0.0001304816,0.0003361242,0.0002194169,0.0005566181,0.00113358],"category_scores_gemma":[0.0001583349,0.0002575404,0.0003303095,0.0001240982,0.0003136556,0.0003529413,0.0001906128,0.001548941,0.0003044974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002613054,"about_ca_system_score_gemma":0.0002396576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000353441,"about_ca_topic_score_gemma":0.0003640311,"domain_scores_codex":[0.999736,0.00004795706,0.00003408063,0.00006230595,0.00004568812,0.00007400088],"domain_scores_gemma":[0.9998005,0.00003171795,0.00005976979,0.00002117436,0.00001414205,0.00007268959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003390222,0.0002546183,0.0001041264,0.00002763809,0.000005494836,0.00003839105,0.00001940013,0.0001464877,0.9983233,0.00009552402,0.00003234025,0.0006135826],"study_design_scores_gemma":[0.000250505,0.003396934,0.002010157,0.00001537741,0.00003880484,0.0003590472,0.00002342463,0.002806069,0.9893849,0.0000879695,0.001618126,0.00000874924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966514,0.0003369123,0.001500258,0.0001092972,0.00003889202,0.0000763721,0.0002656573,0.00009985701,0.000921451],"genre_scores_gemma":[0.9949536,0.0003202481,0.001849773,0.0001051899,0.00002149264,0.00008959258,0.0003601265,0.00003156338,0.002268507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00113358,"threshold_uncertainty_score":0.003792226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01685604807079358,"score_gpt":0.2640052801824214,"score_spread":0.2471492321116278,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}