{"id":"W2618321549","doi":"10.1021/acs.jnatprod.6b01019","title":"Antimalarial Activities of Alkyl Cyclohexenone Derivatives Isolated from the Leaves of <i>Poupartia borbonica</i>","year":2017,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Chicoutimi","funders":"European Regional Development Fund; Conseil Régional de La Réunion; Fonds De La Recherche Scientifique - FNRS; European Commission","keywords":"HeLa; Plasmodium falciparum; Cytotoxicity; Stereochemistry; Quercitrin; Chemistry; In vivo; Quercetin; Ellagic acid; Toxicity; Biology; Biochemistry; In vitro; Pharmacology; Polyphenol; Antioxidant; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003310946,0.0001405493,0.0003025937,0.00001825191,0.0001256807,0.00003246501,0.0006094053,0.0001059277,0.000004730824],"category_scores_gemma":[0.001098602,0.000086163,0.0001240086,0.00004247528,0.0002785071,0.00002457443,0.0001419251,0.000207358,2.361093e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004467726,"about_ca_system_score_gemma":0.0001121512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000383847,"about_ca_topic_score_gemma":0.00001012158,"domain_scores_codex":[0.9990165,0.00008324141,0.0003851483,0.0001769542,0.000200163,0.0001379529],"domain_scores_gemma":[0.9980806,0.00006203702,0.001107577,0.0004787566,0.0002410406,0.0000299864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00112119,0.0001851459,0.003738936,0.0000195351,0.0003183722,0.000007569223,0.00009570525,0.00000240434,0.9925528,0.000002019121,0.001175315,0.0007810053],"study_design_scores_gemma":[0.0005043588,0.0003292066,0.03549051,0.00006794325,0.00008436199,0.00003680858,0.0001489819,0.000006081451,0.9624909,0.0000248786,0.0007159119,0.0001000675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953096,0.002785427,0.000006537904,0.001319885,0.0003314042,0.0000949935,0.00006264968,0.000001733697,0.00008777504],"genre_scores_gemma":[0.9986047,0.0002678269,0.0002603607,0.00002907205,0.0007313453,4.192099e-7,0.00001143487,0.00000819396,0.00008666432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03175157,"threshold_uncertainty_score":0.3513625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01047448958187803,"score_gpt":0.2398109072943707,"score_spread":0.2293364177124927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}