{"id":"W2618529378","doi":"","title":"Comparison of the inhibition of recombinant and native heme oxygenase-1 (HO-1) activity by the imidazoledioxolane compound QC-15","year":2015,"lang":"en","type":"article","venue":"Undergraduate Research Journal","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Recombinant DNA; Heme oxygenase; Heme; Endoplasmic reticulum; Microsome; Chemistry; In vitro; Molecular biology; Biochemistry; Pharmacology; Biology; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001802338,0.0002447011,0.0001929845,0.000121822,0.00005071083,0.0001456942,0.0001466265,0.0001349081,0.0005143738],"category_scores_gemma":[0.0001266469,0.00006966465,0.0001470882,0.000125172,0.0001205898,0.0001252756,0.00005482116,0.0002575542,0.0001110774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001697971,"about_ca_system_score_gemma":0.000144132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000635613,"about_ca_topic_score_gemma":0.0009412209,"domain_scores_codex":[0.9999104,0.00001760511,0.000009926374,0.00001511318,0.0000265124,0.00002054681],"domain_scores_gemma":[0.9998913,0.00003509968,0.00002821872,0.000008734118,0.00001619142,0.00002045223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002115993,0.00004054025,0.0001297659,0.00003190558,0.000006373397,0.000008500549,0.000007702469,0.0001012707,0.9983869,0.00002039576,0.00001262098,0.001042421],"study_design_scores_gemma":[0.000009619219,0.0007552638,0.001790766,0.000001648304,0.000009263823,0.00004175379,0.00000492465,0.0004036592,0.996717,0.000005587171,0.0002585849,0.000001880542],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969851,0.001560701,0.000850382,0.00002258929,0.000009840919,0.000008946367,0.0001286058,0.00001854445,0.0004153023],"genre_scores_gemma":[0.9962049,0.0009137504,0.001383982,0.00001609638,0.00000655206,0.00001079752,0.0004446016,0.000005010108,0.001014334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000635613,"threshold_uncertainty_score":0.001720786,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06838090529254184,"score_gpt":0.3698614000346691,"score_spread":0.3014804947421272,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}