{"id":"W2618767609","doi":"10.1038/ncomms15264","title":"Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis","year":2017,"lang":"en","type":"article","venue":"Nature Communications","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Institut National Du Cancer; Ligue Contre le Cancer; Imperial College London","keywords":"Provirus; Virology; Biology; Gene; Leucosis; clone (Java method); Virus; Lymphoma; Bovine leukemia virus; Leukemia; Cancer research; Genetics; Immunology; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009300916,0.0001880739,0.0001614075,0.0002074366,0.0001643386,0.0003688927,0.0001446895,0.0001941396,0.00131459],"category_scores_gemma":[0.0001429114,0.0001346814,0.0001448458,0.0001125614,0.0002617472,0.0001840655,0.0002163321,0.0005187948,0.000439638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003056035,"about_ca_system_score_gemma":0.0001373968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005616308,"about_ca_topic_score_gemma":0.0009217422,"domain_scores_codex":[0.9998722,0.00001726239,0.000007909379,0.00003941142,0.00004206895,0.00002112767],"domain_scores_gemma":[0.9998693,0.00003037656,0.00004245438,0.00001827856,0.00001553176,0.0000240291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002194276,0.000004619159,0.0002618314,0.000008314256,0.000001009608,0.00002349582,0.00001132288,0.00002276216,0.9991473,0.00008704441,0.000004879023,0.0004056102],"study_design_scores_gemma":[0.00000271619,0.0001370703,0.007057084,0.000002868751,0.000005429747,0.0003564299,0.00003496951,0.000330042,0.9912893,0.00007883328,0.0007030435,0.000002246922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940076,0.000897626,0.003449988,0.00003575414,0.00001548741,0.00001411258,0.0001395555,0.00006619546,0.001373575],"genre_scores_gemma":[0.9976209,0.0003351009,0.001013389,0.00001671161,0.000005608783,0.000005848709,0.0001459761,0.00001205542,0.0008443205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00131459,"threshold_uncertainty_score":0.00439769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0300879760539261,"score_gpt":0.3155945369842801,"score_spread":0.285506560930354,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}