{"id":"W2618842028","doi":"10.1093/neuonc/nox083.180","title":"MEDU-30. GENES PRESERVING STEM CELL STATE IN GROUP 3 MB BTICS CONTRIBUTE TO THERAPY EVASION AND RELAPSE","year":2017,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Medulloblastoma; Biology; Stem cell; Population; Downregulation and upregulation; Cancer research; Gene; Oncology; Internal medicine; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001102261,0.0001594912,0.0002438949,0.0003308838,0.0001894405,0.0003343197,0.00009502357,0.0002199957,0.001934287],"category_scores_gemma":[0.0001153306,0.00005809027,0.0001939134,0.0002001476,0.0001695738,0.0001165778,0.0001786387,0.0003180111,0.0004739232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002773532,"about_ca_system_score_gemma":0.0001844248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006383519,"about_ca_topic_score_gemma":0.001054846,"domain_scores_codex":[0.9999043,0.00001026173,0.000006477225,0.00001867549,0.00003023709,0.00003006984],"domain_scores_gemma":[0.9999193,0.00001030307,0.00002453227,0.000008567354,0.00001083699,0.00002646984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002203056,0.00003024337,0.003735181,0.00003264332,0.000006819449,0.0001333431,0.00008473424,0.00004928393,0.9905494,0.0001366928,0.0001176625,0.004903701],"study_design_scores_gemma":[0.00002862567,0.00149019,0.2210192,0.0000257039,0.00007208569,0.001836483,0.0004022181,0.001349338,0.7579363,0.0003002277,0.01553004,0.000009519063],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954489,0.0009209912,0.0007846708,0.00006211295,0.00001149452,0.00002800315,0.001122461,0.00007000491,0.001551401],"genre_scores_gemma":[0.9946843,0.0003696237,0.000719687,0.00007048928,0.000006104002,0.00005493487,0.00141478,0.0000228481,0.002657275],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001934287,"threshold_uncertainty_score":0.006470859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02410984020784406,"score_gpt":0.2892152730980958,"score_spread":0.2651054328902517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}